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厄贝沙坦治疗慢性心力衰竭疗效观察 被引量:8

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摘要 目的探讨厄贝沙坦治疗慢性心力衰竭(CHF)的临床疗效。方法选择112例慢性充血性心力衰竭患者(心功能II—IV级),随机分为两组:对照组采用常规治疗方法.治疗组在常规治疗的基础上加用厄贝沙坦,疗程6个月。观察治疗前后左室收缩(LVS)、舒张末期内径(LVD),左室射血分数(LVEF)及心功能变化。结果治疗后两组临床疗效显效及总有效率差异有统计学意义(P〈0.05);LVS、LVD、LYEF及6min步行试验差异有统计学意义(P〈0.01)。治疗组治疗前后左室射血分数、6min步行试验均显著提高(P〈0.01),左室收缩、舒张末期内径显著缩小(P〈0.01);对照组治疗前后,左室射血分数、6min步行试验均显著提高(P〈0.01),而左室收缩、舒张末期内径无显著改变(P〉0.05)。结论厄贝沙坦治疗CHF可获得有益的临床疗效,并且有良好的耐受性和安全性。
作者 张小伟
出处 《中国基层医药》 CAS 2010年第7期940-941,共2页 Chinese Journal of Primary Medicine and Pharmacy
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