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自制结肠传输试验用标志物的制备与应用(附50例报告) 被引量:2

The preparation and clinical application of a self-made marker for colonic transit test
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摘要 目的自制一种用于结肠传输功能检查的不透X线标志物。方法利用海藻酸钠和氯化钙反应可生成海藻酸钙膜类似于半透膜的特点,包裹硫酸钡形成不透X线小球(即所制备标志物)。经志愿者测试后临床应用。结果口服后数日,腹部平片上小球仍显影清晰,无假阳性或假阴性,联合排粪造影检查50例功能性便秘患者,结果能对便秘做出准确分型。结论本标志物制备方法简便,成本低,用于结肠传输试验数日内均显影清晰,能用于便秘的分型诊断、指导治疗方案及疗效评价。 Objective To make a kind of Radioopaque maker for examining colonic transit function.Methods Sodium Alginate reacting with Calcium chloride could form calcium alginate membrane which was alike to semipermeable membrane.Then it wrapping up Barium Sulfate could produce globules which was the self-made radioopaque marker.The markers were first used in volunteers and then in patients.Results Several days after oral application,the marker was still clearly visualized on the plain abdominal radiograph,without false positive or false-negative.Using this method combining with defecography in 50 patients who complained of functional constipation,made exact diagnosis in constipated type.Conclusion The preparation of this kind of marker is easy and low-cost;the marker visualizes clear in several days for examining colonic transit function which can be used for diagnosis of constipated type and be helpful in curing and evaluating curative effect.
出处 《胃肠病学和肝病学杂志》 CAS 2010年第4期358-359,共2页 Chinese Journal of Gastroenterology and Hepatology
关键词 自行制备 标志物 结肠传输试验 临床应用 Self-made Marker Colonic transit test Clinical application
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