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氯吡格雷抵抗相关机制及对策 被引量:3

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摘要 氯吡格雷(clopidogrel,CPG)是临床应用最为广泛的新型噻吩吡啶类抗血小板聚集药物之一,其作用明显优于阿司匹林。有研究结果显示,CPG联合阿司匹林比起单用阿司匹林可使非sT段抬高型急性冠脉综合征(ACS)患者的终点事件明显下降。目前,CPG已广泛用于ACS等疾病和经皮冠状动脉介入治疗(PCI)后的抗血栓治疗。然而,大量体外实验证实个体对CPG的反应存在较大的差异性。部分患者尽管长期服用常规剂量的CPG,但临床上仍不能有效地防止血栓事件的发生,
出处 《中国医师进修杂志》 2010年第10期71-74,共4页 Chinese Journal of Postgraduates of Medicine
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同被引文献49

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