摘要
目的:探讨晚期大肠癌3种化疗方案临床疗效和经济效果。方法:对89例晚期大肠癌患者,根据治疗方案不同分为A组(FOLFOX方案)、B组(FOLFIRI方案)、C组(XELIRI方案)。比较3种化疗方案疗效,并运用药物经济学方法进行最小成本分析。结果:A、B、C组的有效率分别为42.1%、46.7%、33.3%(P>0.05),成本分别为12291.7、16933.9、17804.2元。结论:FOLFOX方案治疗晚期大肠癌较经济。
OBJECTIVE：To evaluate the clinical efficacy and economic effect of 3 kinds of chemotherapeutic regimens in the treatment of advanced colorectal cancer. METHODS：89 patients with advanced colorectal cancer were divided into group A（FOLFOX regimen）,group B（FOLFIRI regimen）and group C（XELIRI regimen）. The curative effects of 3 kinds of chemotherapeutic regimens were compared and pharmacoeconomics was applied for cost-minimization analysis. RESULTS：Effective rate of group A,group B and group C were 42.1%,46.7%,33.3%,respectively（P0.05）,and the cost were 12 291.7 yuan,16 933.9 yuan and 17 804.2 yuan,respectively. CONCLUSION：FOLFOX regimen is superior to the other two regimens and has better cost-effectiveness.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第14期1267-1269,共3页
China Pharmacy
关键词
大肠癌
化疗方案
最小成本分析
Colorectal cancer
Chemotherapeutic regimen
Cost-minimization analysis
