摘要
目的探讨微波消融术(MWA)在老年乳腺癌治疗中的应用价值。方法在超声引导下对病理确诊的16例老年女性乳腺癌患者(16个肿瘤)进行MWA治疗,治疗后1、3、6、12个月分别对患者进行随访,观察治疗前后16例患者的肿瘤体积、声像图表现及病理形态学变化,并对患者预后及生存期情况进行分析。结果 16例患者MWA治疗中无皮肤烧伤等严重并发症发生;治疗后即刻,彩色多普勒超声显示16个乳腺肿瘤内血流信号均消失;穿刺活检病理显示肿瘤消融区边缘均呈凝固性坏死表现;治疗后3、6、12个月超声随访,肿瘤体积均逐渐缩小,平均缩小率为(27.2±6.1)%、(55.1±7.4)%及(84.6±8.3)%。声像图表现:治疗后1个月,肿瘤消融区内回声较治疗前均匀减低,边界模糊,形态规则;治疗后6个月,随体积缩小肿瘤边界变清晰,回声均质,形态规则。治疗后1、2、3年患者无瘤生存分别为16例、15例、14例。结论超声引导MWA微创治疗有效、安全,适用于不能耐受手术治疗的老年乳腺癌患者。
Objective To study the clinical value of microwave ablation （MWA）in the elderly patients with breast cancer under the guidance of ultrasound. Methods Under the screening of dynamic altrasound,16 cases of breast neoplasms in 16 elderly women diagnosed as breast cancer by pathologic examination were treated with MWA. The curative effects, pathologic and sonographic changes were recorded. Results After the treatment, 16 cases of cancers were demonstrated by pathologic examination to be necrotic in situ and the hemodynamic signal was disappeared in CDFI. The treatment time was 32.4 ± 11.6 min without severe complications. The volume of neoplasms was 1.76 ± 1.55 cm^3 before therapy. While within 1 month during follow-up visits, they were 1.83 ± 1.59 cm^3 with the echo reduced and the border unsharp. The neoplasms were gradually minished 1 mouth later during follow-up visits. The volume of neoplasms was obviously diminished （ P 〈 0. 05 ） in 3,6, 12 months during follow-up visits and the minifications were （27.2 ±6. 1 ）% , （55. 1 ± 7.4）% , （84.6 ± 8.3）% , respectively. The tumor-free survival patients in the 1,2,3 years were 16,15,14, respectively . Conclusions Breast cancers can be accurately positioned and mehed with MWA under the screening of ultrasound, which is minimal invasive, easy to access and cost saving, especially for the operation-intolerant patients.
出处
《中华医学超声杂志（电子版）》
2010年第1期39-42,共4页
Chinese Journal of Medical Ultrasound(Electronic Edition)
关键词
乳腺肿瘤
超声检查
微波
短波疗法
Breast neoplasms
Uhrasonography
Microwaves
Short-wave therapy
