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营养学新进展 被引量:12

Advances in science of nutrition
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摘要 目的分析近5年国内外营养学发展现状,为确定今后营养学的研究方向提供参考。方法采用情报调研方法,检索相关文献,预测热点问题,提出本专业发展需求及设想。结果过去5年,营养基因组学、转录组学、蛋白质组学和营养代谢组学、系统生物学等新概念和新技术在营养学领域得到了广泛应用。通过这些技术,可以从分子水平探索营养素对基因和蛋白质表达的影响,也可以反观基因改变对营养相关性疾病发生的影响。临床营养治疗的进展也为多样化的临床治疗以及患者的尽早康复提供了可能。目前我国营养学领域存在教育体系不健全,专业人才匮乏,对营养学发展的重要性认识不足,营养信息标准化和规范化建设滞后等问题。结论未来5年营养学的发展应坚持个体营养与整体营养并重。由此派生出的一系列分子生物学和系统生物学研究将大大提高国民的身体素质和健康基础水平。 Objective To analyze the development status worldwide of nutriology,so as to provide an orientation of its development in the future.Methods The professional articles published were retrieved by information research methods to predict the focal problem,and to provide the demand and presumption of nutriology development.Results In the past 5 years,some innovative concepts and technics were widely used in nutrition studies,such as nutritional genomics,nutritional proteomics and systematic biology,etc.These technologies made it possible to study the influences of nutrients on gene and protein expression,and reversely,the influences of gene changes in nutrient related disturbances in metabolism.Advances in clinical nutritional therapy provides patients with a variety of clinical treatment and the possibility of earty rehabilitation.At present,there are some problems in the fields of nutritional therapy in our country,such as a lack of resource of professional staff,imperfect education system,deficiency in understanding the importance of nutriology,and the lag of standardization and normalization of nutrition information.Conclusions The progress of nutriology in coming five years should lay stress on the parallel development of individual and nationwide health level.A series of studies in molecular biology and systematic biology will upgrade the national physical quality and the basic health condition of population nationwide.
作者 蔡东联 林宁
出处 《解放军医学杂志》 CAS CSCD 北大核心 2010年第4期360-363,共4页 Medical Journal of Chinese People's Liberation Army
关键词 基因组学 蛋白质组学 系统生物学 营养生理学 genomics proteomics systems biology nutrition physiology
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