摘要
HBV-DNA总称为乙型肝炎病毒（HBV）脱氧核糖核酸（DNA）。HBV-DNA载量则是乙型肝炎病毒感染最直接、特异性较强和灵敏度高的指标。近几年国内外众多学者开始关注HBV-DNA载量的相关性研究。对HBV-DNA载量的检测分析，可以了解乙型肝炎疾病的活动情况；预测患肝细胞癌的风险或肝脏相关疾病的病死率；分析乙型肝炎患者是否需要接受抗病毒治疗及治疗方案的选择；评估和预测药物的疗效。由此可见，HBV-DNA载量在乙型肝炎的临床诊治中扮演着重要的角色。
HBV DNA-load is a sensitive and specific marker in clinical diagnosis for HBV infection. Recent years, HBV DNA-load have been paid attention in the field. Analysis of HBV DNA-load is helpful for learning the activity of hepatitis, for predicting the risk of HCC and death rate of liver-related disease, for determining whether the CHB patient need to receive antiviral treatment and what regimen of treatment should be selected, for assessing and predicting the drug efficacy. Therefore, HBV DNA-load plays an important role in clinical diagnosis and treatment for CHB.
出处
《世界感染杂志》
2010年第1期51-55,71,共6页
World Journal of Infection
关键词
HBV-DNA
肝纤维化
肝硬化
肝癌
HBV-DNA
Liver fibrosis
Liver cirrhosis
Hepatocellcular carcinoma
