摘要
前列腺素是一类由花生四烯酸通过环氧化酶途径合成的脂类介导物。在哺乳动物排卵、受精、胚泡植入、蜕膜化、子宫平滑肌收缩、黄体退化及卵泡发育过程中起重要作用。对于家禽,前列腺素促进其产卵和子宫收缩;在产卵中期,卵巢静脉血浆中前列腺素的浓度为外周血浆浓度的5～20倍。这种高剂量、脉冲式分泌的前列腺素不仅能促进家禽成熟卵泡的排卵,而且可作为促性腺激素的第二信使介导颗粒细胞对cAMP的反应,促进了等级前卵泡颗粒细胞的增殖,进而在优势卵泡的选择过程中起重要作用。
Prostaglandins（PGs） are a group of lipid mediators,which were synthesized by the cyclooxygenase（COX） pathway from arachidonic acid.In mammals,it has been proved that PG plays a number of essential roles in reproductive processes,such as ovulation,fertilization,implantation,decidualization,uterus smooth muscle contraction,luteal regression and follicle development.In the hen,administration of PG induces oviposition and stimulates uterine contractility.At midsequence of ovipositions,the concentration of PG in the ovarian venous plasma was 5 to 20 times higher than in peripheral plasma.PG was released in a pulsate format in the avian,this not only stimulates uterine contractility,but also acted as the second messenger of gonadotropins for cAMP action in the granulosa cells＇ proliferation.Hence,the change of PG content in follicle fluid played an important role in prehierarchical follicle selection.
出处
《中国畜牧兽医》
CAS
北大核心
2010年第4期138-142,共5页
China Animal Husbandry & Veterinary Medicine
基金
山东大学威海分校人才工程(0000507300034)
关键词
前列腺素
等级卵泡
卵泡发育
禽类
prostaglandins
prehierarchical follicle
follicle development
avian
