摘要
目的:探讨原发性胃淋巴瘤的临床特点和治疗方法。方法:回顾性分析我院50例原发性胃淋巴瘤患者的临床资料,总结其诊断与治疗方法。50例中,根治性切除43例,其中胃大部切除38例(D114例,D224例),全胃切除5例;姑息性切除4例,剖腹探查3例。术后46例接受辅助放、化疗。所有病例均经组织病理学检查证实。结果:本组共有46例获得随访,总体5年生存率为78%。原发性胃淋巴瘤误诊率高,对放、化疗较为敏感,治疗上采用手术为主的综合疗法,可提高生存率。结论:原发性胃淋巴瘤的术前诊断主要依靠胃镜和CT检查。早期原发性胃淋巴瘤治疗上采取以手术为主,加放疗、化疗的综合治疗方案;晚期原发性胃淋巴瘤主要采取非手术疗法。
Objective: To investigate the diagnosis and treatment methods of primary gastric lymphorna (PGL). Methods:Clinical data of 50 PGL patients identified by postoprative pathology in our hospital were analyzed retrospectively; 43 cases of 50 patients did radical operation, 38 cases underwent subtotal gastrectomy, 5 cases underwent total gastrectomy;4 cases underwent palliative resection and 3 cases underwent exploratory laparotorny only. Postoperatively 46 cases received adjuvant treatment (chemotherapy and/or radiotherapy). All cases were identified by postoprative pathology. Results: 46 cases were followed-up survey, the overall 5-years survival rate of these patients were 78 %. The misdiagnosis rate is high. Chemotherapy and radiotherapy are sensitive for PGL. It can improve survival rate by adopting the composite treatment in which operation is major. Conclusion:The preoperative diagnosis in PGL relies mainly on gastroscopy with biopsy and CT scan. For patients with early stage dieases, radical resection combined with adjuvant therapy is the key factor, chemotherapy or/and radiotherapy is useful management for patients with advanced stage disease. KEY WORDS Lymphoma, Diagnosis, Treatment, Surgical operation
出处
《医学理论与实践》
2010年第4期377-379,共3页
The Journal of Medical Theory and Practice
关键词
淋巴瘤
诊断
治疗
外科手术
Lymphoma, Diagnosis, Treatment, Surgical operation