摘要
目的:观察中药外洗方联合弥可保治疗糖尿病周围神经病变的疗效。方法:将62例患者随机分为治疗组34例与对照组28例,在基础治疗相同的情况下,对照组单用弥可保口服治疗,治疗组给予中药外洗方联合弥可保治疗。观察患者症状、体征的改善情况及神经传导速度的变化。结果:临床疗效总有效率治疗组为88.2%,对照组为64.3%,2组比较,差异有显著性意义(P<0.05),提示治疗组疗效优于对照组。治疗后治疗组正中神经与腓总神经的运动传导速度(M NCV)、感觉传导速度(SNCV)均较治疗前显著增加,差异均有非常显著性意义(P<0.01);对照组腓总神经SNCV较治疗前显著增加,差异有显著性意义(P<0.05)。治疗后2组各指标比较,差异均有非常显著性意义(P<0.01)。提示改善神经传导速度,治疗组优于对照组。结论:中药外洗方联合弥可保治疗糖尿病周围神经病变能减轻患者的临床症状,改善其神经传导速度。
Objective:To observe the therapeutic effect of external application of herbal medicated liquid combined with oral use of methycobal for the treatment of diabetic peripheral neuropathy(DPN).Methods:Sixty-two qualified patients were randomized into the treatment group and the control group.Both groups received routine basic treatment,and additionally the control group received oral use of methycobal and the treatment group received external application of herbal medicated liquid combined with oral use of methycobal.The improvement of symptoms and signs as well as the changes of nerve conduction velocity(NCV) was observed.Results:The total effective rate was 88.2% in the treatment group and 64.3% in the control group,the difference being significant between the two groups(P < 0.05).The motor NCV and sensory NCV were increased in the treatment group after treatment(P < 0.01 compared with those before treatment).The sensory NCV of common peroneal nerve in the control group after treatment differed from that before treatment(P < 0.05).After treatment,the differences of motor NCV and sensory NCV were significant between the two groups(P < 0.01),indicating that the improvement of NCV was better in the treatment group than that in the control group.Conclusion:External application of herbal medicated liquid combined with oral use of methycobal can relieve the symptoms and improve NCV of diabetic peripheral neuropathy patients.
出处
《新中医》
CAS
北大核心
2010年第4期27-28,共2页
New Chinese Medicine
