摘要
目的观察沙美特罗联合氟替卡松治疗支气管哮喘的临床效果。方法90例支气管哮喘患者随机分为治疗组和对照组各45例。对照组予以抗感染、吸氧、止咳化痰等综合治疗,治疗组在对照组基础上联合应用丙酸氟替卡松和沙美特罗吸入治疗,分别在治疗前和治疗3个月后进行1s用力呼气容积(FEV1)、用力肺活量(FVC)和呼气峰流量(PEF)测定。并对哮喘症状进行评分。结果2组治疗后FEV1、FVC、PEF均升高,差异均有统计学意义(P<0.05),且治疗组改善情况优于对照组,差异均有统计学意义(P<0.05);2组治疗后哮喘症状评分均降低,差异均有统计学意义(P<0.05),且治疗组改善情况优于对照组,差异有统计学意义(P<0.05)。结论联合吸入沙美特罗和氟替卡松治疗支气管哮喘能够达到哮喘控制,具有良好的疗效。
Objective To observe clinical effect of salmeterol and fluticasone in treatment of bronchial asthma.Methods 90 patients with bronchial asthma were randomly divided into treatment group and control group,45 cases of each.The control group was given anti-infection,oxygen,cough phlegm and other comprehensive treatment,the treatment group on the basis of the control group combined fluticasone propionate and salmeterol inhalation therapy,FEV1,FVC,PEF were measured before treatment and 3 months after,and asthma symptoms were scored.Results FEV1,FVC,PEF of the two groups were higher after treatment,the differences were statistically significant（P〈0.05）,and the improvements in the treatment group were better than the control group,the differences were statistically significant（P〈0.05）;Asthma symptom scores of the two groups were lower after treatment,the differences were statistically significant（P〈0.05）,and the improvements in the treatment group was better than the control group,the difference was statistically significant（P〈0.05）.Conclusion Inhaled salmeterol and fluticasone propionate in treatment of bronchial asthma,asthma control can be achieved with good effect.
出处
《临床合理用药杂志》
2010年第6期22-23,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
沙美特罗
氟替卡松
支气管哮喘
临床观察
Salmeterol
Fluticasone
Bronchial asthma
Clinical observation
