摘要
目的:探讨电针对改善抑郁症认知功能的作用。方法:将93例首发抑郁症患者随机分为帕罗西汀加合用电针组(合用电针组)48例,单纯帕罗西汀组(单纯药物组)45例,观察3周。于治疗前及治疗3周采用汉密顿抑郁量表(HAMD)、事件相关点位P300,评定临床疗效及认知功能改善情况。结果:治疗3周合用电针组有效率89.6%,单纯药物组为80%(P<0.05)。治疗后HAMD评分、P300潜伏期均显著低于治疗前(P<0.05);两组治疗后P300波幅均明显高于治疗前(P<0.05);治疗后合用电针组P300波幅明显高于单纯药物组(P<0.05),合用电针组P300潜伏期明显低于单纯药物组(P<0.05)。结论:电针治疗对改善抑郁症认知功能有显著增效作用。
Objective：To explore the effect of electro-acupuncture therapy on depression with cognitive function. Method-93 cases of first-episode depression patients were randomly divided into acupuncture group of 48 cases receiving paroxetine plus electro-acupuncture and drug group of 45 cases doing single pure paroxetine only. Clinical efficacy and the improvement of cognitive function were assessed with the Hamilton depression scale （HAMD） and the event-related potential P300 before treatment and at the end of the 3rd week treatment. Results：At the end of the 3rd week,effective rates were respectively 89.6% in acupuncture group compared with drug group of 80% （ P 〈 0.05 ） while the total scores of the HAMD and the latency of P300 lowered significantly in both groups （ P 〈 0.05 ） ; the P300 amplitude were significantly hoisted than pretreatment in two groups（ P 〈 0.05 ） ; after treatment, the P300 amplitude of acupuncture group was significantly higher than drug group （ P 〈 0.05 ）, the P300 latency of A group was significantly lower than drug group （P 〈 0.05 ）. Conclusion：Electro-acupuncture therapy have significant effect on depression with cognitive function.
出处
《临床精神医学杂志》
2010年第2期123-125,共3页
Journal of Clinical Psychiatry
关键词
抑郁症
帕罗西汀
电针
depression
paroxetine
electro-acupuncture
