摘要
目的:探讨万拉法新治疗抑郁症的疗效与安全性。方法:将102例抑郁症患者随机分为两组,万拉法新组52例,阿米替林组50例,疗程8周,用汉密尔顿抑郁量表(HAMD)、副反应量表(TESS)评定疗效和不良反应。结果:万拉法新与阿米替林的总疗效比较,差异无统计学意义;万拉法新主要不良反应少于阿米替林。结论:万拉法新是一种安全、有效的抗抑郁药。
Objective:To explore the efficacy and safety of Venlafaxine in the treatment of depression. Methods:102 cases of depression were randomly assigned into Venlafaxine group (n=52) and Amitriptyline group (n=50),the course of treatment was 8 weeks. The effects and side reactions were evaluated with Hamilton depression scale (HAMD) and treatment emergent symptom scale (TESS). Results:There was no significant difference in effectiveness between two groups. Venlafaxine had fewer side effects than Amitriptyline. Conclusion:Venlafaxine is a safe and effective antidepressant.
出处
《中国医药导报》
CAS
2010年第11期60-61,共2页
China Medical Herald