摘要
利用人ＧＣＳＦ基因组基因和ｃＤＮＡ基因作为目的片段，将其受控于２．６ｋｂ的小鼠乳清酸蛋白（ＷＡＰ）基因的调控区下，通过显微注射法获得了两只整合有人ＧＣＳＦ转基因小鼠，通过繁殖建立了稳定的转基因系．一些表型参数测定表明，转基因鼠与正常鼠无明显差别。
Several hybrid genes that whey acid protein(WAP) gene directed human G CSF genomic DNA and cDNA were constructed to produce transgenic mice. Two transgenic mice were obtained by microinjection method and the transgenic mouse lines were established. Some parameters, including body weight and some blood materials were determined. The result showed that there were no differences between transgenic and normal mice in those parameters.
出处
《应用与环境生物学报》
CAS
CSCD
1998年第4期364-367,共4页
Chinese Journal of Applied and Environmental Biology
基金
国家"863"高技术项目
