摘要
利用核磁共振碳谱、磷谱、氢谱对甘氨酸法合成草甘膦的各阶段反应进行定量跟踪分析,发现由甲醛引起的副反应是影响草甘膦收率的重要因素之一,证实了羟甲基亚瞵酸、增甘膦、N-甲基草甘膦和亚磷酸是甘氨酸法合成草甘膦的主要副产物,减少或抑制其生成是草甘膦合成工艺优化的关键。探讨了抑制副反应发生的条件,对甘氨酸法合成草甘膦工艺优化有重要的理论指导意义。
It was found that the side-reactions caused by formaldehyde is an important influence factor in the synthesis of glyphosate started from glycine by analysis with ^13C NMR, ^31p NMR, and ^1H NMR. Hydroxymethyl phosphonic acid, Polaris, N-（methylation） glyphosate and phosphite were the main byproducts and reducing or restraining the generation of them is the crux of optimizing glyphosate technique. Optimizing the technique of synthesizing glyphosate starting from glycine has great significance in theory.
出处
《农药学学报》
CAS
CSCD
北大核心
2010年第1期37-41,共5页
Chinese Journal of Pesticide Science
