摘要
目的分析我国成人中糖尿病家族史阳性率及其特点。方法对１９９４年我国２５岁以上２５万人群糖尿病调查中进行口服葡萄糖耐量试验（ＯＧＴＴ）（７５克）后诊断的糖尿病２７６７例和糖耐量正常的８６７４例进行比较。结果糖尿病人群中糖尿病家族史阳性率为１４．０％，正常人群有糖尿病家族史者为７．４％，两者有显著性差异（Ｐ＜０．００１）。糖尿病人群中父亲、母亲糖尿病家族史阳性率分别为３．４％、４．０％，两者无差异。有糖尿病家族史的糖尿病患者３３．６％发病年龄在２５～４４岁间，３３．１％在４５～５４岁段，另３３．３％的糖尿病患者发病年龄在５５岁以上。而无糖尿病家族史的糖尿病患者５０．２％在５５岁以后发病。家族史阳性组腰臀围比（ＷＨＲ）及收缩压均低于阴性组。结论有糖尿病家族史的糖尿病患者发病年龄早，而无糖尿病家族史的糖尿病患者发病年龄晚，且向心性肥胖，收缩压升高更明显。
Objective To evaluate the prevalence and characteristics of family history in Chinese adult diabetics. Methods Data were drawn from the national diabetes survey in 1994 in which 250000 adults over 25 were studied. After oral glucose tolerance test (OGTT) (75g), there were 2767 diabetics, while 8674 individuals showed normal OGTT. Results The prevalence of positive family history was 14.0% among the diabetics and 7.4% among those with normal OGTT (P<0.001). The positive rates of maternal and paternal family history were 3.4% and 4.0% respectively in diabetes group (P>0.05). 33.6% of the diabetics with positive family history developed the disease between 25 44 years of age, 33.1% between 45 54 and only 33.3% after 55. 50.2% of the patients without positive family history developed diabetes after 55. Both WHR and systolic pressure of patients with positive family history were lower than those without family history. Conclusion The age of onset of diabetes was younger in petients with positive family history than in those without family history and the patients without positive family history had an obvious tendency of central obesity and high systolic pressure.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
1998年第6期361-364,共4页
Chinese Journal of Endocrinology and Metabolism
关键词
糖尿病
家族史
阳性率
Diabetes mellitus Family history
