摘要
乳腺原位癌一直是肿瘤病理学领域的研究热点。虽然关于乳腺原位癌的研究报告已经有很多,但是近年来一些新的进展很值得关注,例如:乳腺导管内癌(DCIS)的分子亚型、细胞遗传学、进展途径、临床诊断和治疗等方面的研究;乳腺小叶原位癌(LCIS)的克隆性、染色体变化及变异类型的研究;以及DCIS和LCIS关系的研究等。在此综述如下。
出处
《中华医学杂志》
CAS
CSCD
北大核心
2010年第8期570-573,共4页
National Medical Journal of China
基金
国家自然科学基金资助项目(30872519)
天津市自然科学基金(09JCYBJC10100)
教育部长江学者和创新团队计划(TRT0743)
参考文献32
-
1O'Flynn EA,Morel JC,Gonzalez J,et al.Prediction of the presence of invasive disease from the measurement of extent of malignant microcalcification on mammography and ductal carcinoma in situ grade at core biopsy.Oin Radiol,2009,64:178-183. 被引量:1
-
2Meijnen P,Peterse JL,Antonini N,et al.Immunohistochemicalcategorisation of ductal carcinoma in situ of the breast.British J Cancer,2008,98:137-142. 被引量:1
-
3Bryan BB,Schnitt SJ,Collins LC,et al.Ductal carcinomain situ with besal-iike phenotype,a possible precursor to invasive basallike breast cancer.Mod Pathol,2006,19:617-621. 被引量:1
-
4Steinman S,Wang J,Bourne P,et al.Expression of cytokeratin markers,ER-alpha,PR,HER-2/neu,and EGFR in pure ductal carcinoma in aim(DCIS)and DCIS with co-existing invesive ductal carcinoma(IDC)ofthe breast.Ann Clin Lab Sci,2007,37:127-134. 被引量:1
-
5陈健,张旭,田茹,郭瑞峰,梁化印,董红梅.乳腺导管内癌分子分型应用研究[J].临床与实验病理学杂志,2009,25(1):29-32. 被引量:10
-
6Tsikitis VL,Chung MA.Biology of ductal carcinoma in situ classification based on biologic potential.Am J Clln Oncol,2006,29:305-310. 被引量:1
-
7Tavaesoli FA,Eusebi V.AFIP Atlas of tumor pathology.series 4 (Tumors of the mammary gland).Washington,DC:American Registry of Pathology and Armed Force Institute of Pathology,2009:54-71. 被引量:1
-
8Gao Y,Niu Y,Wang X,et al.Genetic changes at specific stages of breast cancer progression detected by comparative genomic hybridization.J Mol Med,2009,87:145-152. 被引量:1
-
9Alexe G,Dalgin GS,Scanfeld D,et al.Breast cancer stratification from analysis of micro-array data of micro-dissected specimens.Genome Inform,2007,18:130-140. 被引量:1
-
10Daigin GS,Alexe G,Scanfeld D,et al.Portraits of brenst cancer progression.BMC Bioinformatics,2007,8:291. 被引量:1
二级参考文献17
-
1Perou C M, Serlie T, Eisen M B, et al. Molecular portraits of human breast turnouts[ J ]. Nature ,2000,406 ( 6797 ) :747 - 752. 被引量:1
-
2Rakha E A, EI-Sayed M E, Green A R,et al. Breast carcinoma with basal differentiation : a proposal for pathology definition based on basal cytokeratin expression[ J]. Histopathology,2007,50(4) :434 -438. 被引量:1
-
3Sorlie T, Perou C M, Tibshirani R. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications[J]. Proc Natl Acad Sci USA, 2001,98 (19):10869 - 10874. 被引量:1
-
4Livasy C A, Karaea G, Nanda R,et al. Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma [ J ]. Mod Pathol, 2006,19(2) :264 -271. 被引量:1
-
5Fulford L G,Easton D F,Reis-Filho J S,et al. Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast [ J ]. Histopathology,2006,49 ( 1 ) : 22 -34. 被引量:1
-
6Dabbs D J,Chivukula M ,Carter G,et al. Basal phenotype of ductal carcinoma in situ : recognition and immunohistologic profile [ J ]. Mod Pathol,2006,19( 11 ) :1506 - 1511. 被引量:1
-
7Bryan B B,Schnitt S J,Collins C L. Ductal carcinoma in situ with basal-like pbenotype: a possible precursor to invasive basal-like breast cancer [ J ]. Mod Pathol,2006,19 ( 5 ) : 617 - 621. 被引量:1
-
8Livasy C A, Perou C M, Karaca G, et al. Identification of a basallike subtype of breast ductal carcinoma in situ [ J ]. Hum Pathol, 2007,38 ( 2 ) : 197 - 204. 被引量:1
-
9Carey L A, Perou C M, Livasy C A,et al. Race, breast cancer subtypes and survival in the Carolina breast cancer study[ J ]. JAMA, 2006,295 ( 21 ) :2492 - 2502. 被引量:1
-
10Li H, Cherukuri P, Li N, et al. Nestin is expressed in the basal/ myoepithelial layer of the mammary gland and is a selective marker of basal epithelial breast tumors [ J ]. Cancer Res, 2007,67 ( 2 ) : 501 -510. 被引量:1
共引文献9
-
1路红,付丽.乳腺导管内癌的影像学与病理学对照研究进展[J].中华乳腺病杂志(电子版),2010,4(6):5-8. 被引量:13
-
2陈健,张旭,田茹,刘艺,董红梅,郭瑞峰,梁化印.CK5表达在基底细胞样乳腺癌诊断中的价值[J].中国现代医学杂志,2011,21(23):2874-2877.
-
3陆春燕,吕凤菊,陈浩华,张红梅,才秋敏.浸润性乳腺癌分子亚型患者的临床特征及预后研究[J].实用医学杂志,2012,28(5):765-767. 被引量:8
-
4舒畅,朱丽.乳腺浸润性导管癌分子分型与预后之间的关系研究[J].中国医药导报,2013,10(16):103-104. 被引量:2
-
5张会丽,常才.乳腺导管原位癌临床特点及其影像学诊断价值[J].肿瘤影像学,2013,22(2):99-103. 被引量:12
-
6汤俊,赵涓涓,张军,张弘,刘黎明.乳腺癌分子亚型中细胞周期素D1的表达及其与雌、孕激素受体的关系[J].中华实验外科杂志,2014,31(5):968-970. 被引量:6
-
7赵涓涓,张弘,汤俊,张军.乳腺癌分子亚型中肺耐药蛋白和多药耐药蛋白的表达及其意义[J].中华实验外科杂志,2015,32(6):1391-1393. 被引量:1
-
8胡玲,程文,韩雪,邵华,孙一欣,王秋程,孔祥崇,董婧.超声引导下空芯针穿刺活检对乳腺浸润性导管癌组织学分级的临床价值[J].现代肿瘤医学,2015,23(13):1846-1849. 被引量:8
-
9陈健,田茹,刘艺,董红梅,郭瑞峰,梁化印.乳腺导管内癌与浸润性导管癌分子表型的关系[J].临床与实验病理学杂志,2015,31(8):877-879. 被引量:1
同被引文献65
-
1许良中,杨文涛.免疫组织化学反应结果的判断标准[J].中国癌症杂志,1996,6(4):229-231. 被引量:1365
-
2韦佳明,刘治滨.乳腺导管内癌的腋窝淋巴结转移率与术式选择[J].中国癌症杂志,2004,14(5):472-473. 被引量:5
-
3Mokbel K. Current management of ductaI carcinoma in situ of the breast[J]. Int J Clin Oneol, 200a, 8 (1) .- 18-22. 被引量:1
-
4Mossa-Basha M, Fundaro GM, Shah BA, et al. Ductal carcinoma in situ of the breast:MR imaging findings with histopathologlc cor- relation[J]. Radiographics, 2010,30(6) : 1673-1687. 被引量:1
-
5Jansen SA,Newstead GM, Abe H,et al. Pure ductal carcinoma in situ: kinetic and morphologic MR characteristics compared with mammanographic MR appearance and nuclear grade[J]. Radiolo- gy,2007,245(3) :684- 691. 被引量:1
-
6任国胜,厉红元,BrettesJ.乳腺小叶原位癌:当前的概念和争论(附145例分析报告)[J].内分泌外科,2006,5(4):9-12. 被引量:1
-
7Menell JI-I, Morris EA, Dershaw DD, et al. Determination of the presence and extent of pure ductal carcinoma in situ by mammog- raphy and magnetic resonance imaging[J] Breast J, 2005,11 (6): 382-390. 被引量:1
-
8Bazzocchi M, Zuiani C, Panizza P, et al. Contrast-enhanced breast MRI in patients with suspicious microcalcifications on mammogra- phy: results of a multicenter trail [J]. AJR, 2006,186 ( 6 ) :1723- 1732. 被引量:1
-
9Ouidi AJ,Schnitt SJ, Fischer L, et al. Vascular permeability fac- tor (vascular endothelial growth factor) expression and anglo- genesis in patients with ductal carcinoma in situ of the breast[J]. Cancer, 1997,80(10) : 1945-1953. 被引量:1
-
10Jansen SA, Paunesku T, Fan X, et al. Ductal carcinoma in situX ray fluorescence microscopy and dynamic contrast-enhanced MR imaging reveals gadolinium uptake within neoplasticmammary ducts in a murine model[J]. Radiology, 2009,253 (2) : 399-406. 被引量:1
引证文献7
-
1颜承平,姜楠,张宗明.乳腺导管内原位癌术后左锁骨上淋巴结转移一例报道[J].中华乳腺病杂志(电子版),2011,5(3):24-24. 被引量:2
-
2钟琰,吴爱国,纪术峰,沈三弟.短发夹RNA沉默促肝细胞再生磷酸酶-3基因表达对乳腺癌MCF-7细胞生长和侵袭能力的影响[J].中华乳腺病杂志(电子版),2011,5(3):29-34. 被引量:1
-
3王岸飞,张焱,程敬亮,胡瑛,荆彦平,王晓燕,孟方方.乳腺原位癌MRI表现和诊断价值[J].放射学实践,2012,27(11):1204-1207. 被引量:5
-
4华兴,黄笑笑,廖泽晓,冼其,于莉娜.乳腺肿瘤间质重构中间质成纤维细胞的免疫表型转换及其临床意义[J].中华肿瘤杂志,2014,36(11):834-838. 被引量:2
-
5杨艳,许国宇,敖国昆,董莘,吴宁,常青.3.0T磁共振DCE与DWI诊断乳腺疾病的对照研究[J].中国医学装备,2015,12(11):86-89. 被引量:6
-
6宋会明,郑媛媛,金燕燕,王谷一.BI-RADS超声联合乳腺X线摄影分级诊断乳腺原位癌的临床应用价值[J].医学影像学杂志,2016,26(4):734-736. 被引量:18
-
7黄智亮.磁共振表观扩散系数等在乳腺导管原位癌中的应用[J].中国现代医生,2017,55(3):98-100.
二级引证文献34
-
1杨春霞,李毅,吕艳丽,殷艳宇,赵越,杨桂花.BI-RADS分级对乳腺X射线摄影联合超声检查诊断乳腺原位癌的临床应用价值分析[J].中华肿瘤防治杂志,2019,26(S01):33-33. 被引量:3
-
2王振龙,崔舜瑀,李万丰,于龙飞.关于乳腺小叶原位癌外科治疗进展探究[J].现代养生,2014,0(14):75-75. 被引量:1
-
3隋良芝.乳腺导管内原位癌术中腋窝淋巴结清扫必要性探讨[J].湖北民族学院学报(医学版),2011,28(4):50-52.
-
4苟凌云,刘健.早期乳腺癌的影像学诊断进展[J].中华临床医师杂志(电子版),2013,7(14):167-169. 被引量:12
-
5韩露,张伟,王慧颖,刘丹青,郭启勇.单纯乳腺导管原位癌(DCIS)MRI特征与HER2表达及病理核分级的相关性研究[J].放射学实践,2015,30(6):643-646. 被引量:3
-
6陈颖,英华.磁共振DWI和ADC在子宫内膜癌诊断中的应用研究[J].中国医学装备,2016,13(1):81-84. 被引量:24
-
7赵佐芳,王宁,王大庆,兰长骏.眼睑基底细胞癌相关成纤维细胞与正常成纤维细胞形态与生长增殖特性差异[J].眼科新进展,2016,36(4):327-330. 被引量:9
-
8黄智亮.磁共振表观扩散系数等在乳腺导管原位癌中的应用[J].中国现代医生,2017,55(3):98-100.
-
9孟祥潮,蔡准,陈国福,吴丽君,张雪鹏.ADAM17-shRNA对人乳腺癌MCF-7细胞增殖的影响及机制[J].山东医药,2017,57(4):21-24. 被引量:12
-
10江桂琼,梁伟翔.BI-RADS超声与乳腺X线摄影联合检查在诊断乳腺原位癌中的价值分析[J].中国当代医药,2017,24(9):92-94. 被引量:3
-
1隋琳倩.乳腺小叶原位癌患者血清VEGF及MMP相关指标的表达研究[J].中国医药指南,2016,14(20):125-125.
-
2范治璐,刘用檝,李荫田,刘辉,杨文.膀胱癌患者染色体变化的特点[J].临床泌尿外科杂志,1995,10(3):181-181.
-
3温昌祥,陶荣亚,梁玉华,宋光江.慢性粒细胞白血病的染色体变化[J].泰山医学院学报,1990,11(3):197-199.
-
4万加华.肿瘤染色体变化的临床意义[J].实用肿瘤杂志,1990,5(4):250-253.
-
5孙琨,严福华,陈克敏,柴维敏.乳腺小叶原位癌的X线和超声及MRI表现[J].放射学实践,2014,29(10):1120-1122. 被引量:6
-
6高凤兰,宋国华.胸腹水染色体变化与恶性肿瘤的关系[J].山东医药,2005,45(25):44-44. 被引量:4
-
7王振龙,崔舜瑀,李万丰,于龙飞.关于乳腺小叶原位癌外科治疗进展探究[J].现代养生,2014,0(14):75-75. 被引量:1
-
8朱勐,彭玉兰,马步云,步宏.乳腺小叶原位癌与小叶非典型增生的高频超声特征分析[J].四川大学学报(医学版),2017,48(2):302-305. 被引量:5
-
9齐华,陈迪,连建华,游文凤,刘运卿,郑江,张云普,王怀立,邹典斌.25例急性非淋巴细胞白血病(ANLL)特异性染色体变化的研究[J].当代医师,1996,1(3):26-27.
-
10常利利,张丽娜,顾林.乳腺小叶原位癌:16例患者的临床特征、诊治及预后[J].肿瘤,2016,36(4):424-429.