摘要
目的观察复方真武冲剂对慢性充血性心力衰竭(CHF)患者中医证候、血浆超敏C反应蛋白(CRP)和心钠肽(ANP)的影响。方法40例CHF患者(NYHA分级为Ⅱ～Ⅳ级)随机分为两组,对照组采用常规CHF治疗;治疗组常规治疗药物同对照组,但剂量为对照组的1/2～2/3,并加服复方真武冲剂;两组疗程均为2周。比较两组中医证候、血浆hs-CRP、ANP改善情况。结果治疗组中医证候总有效率95.00%,对照组为75.00%,两组比较差异有统计学意义。治疗后两组血浆hs-CRP、ANP水平均降低,治疗组降幅高于对照组。结论复方真武冲剂对CHF患者中医证候、神经内分泌过度激活以及炎症过程均有一定的干预作用。
Objective： To observe the effects of Fufangzhenwu Electuary on TCM syndrome, plasma high sensitivity C-reactive protein （hs-CRP） and atrial natriuretic peptide （ANP） in patients with CHF. Methods： Forty patients with CHF （NYHA classⅡ-Ⅳ ） were randomly divided into two groups. Both groups were treated by conventional therapy and the treatment course was two weeks. The treatment group was added with Fufangzhenwu Electuary, but the conventional therapy dosages were only 1/2-2/3 to the control group. The syndrome, the physical signs of TCM, the blood plasma levels of hs-CRP and the ANP were observed. Results： The total effective rate of TCM symptom in the treatment group was 95.00% and the control group was 75.00%. The levels of hs-CRP and ANP in both groups were decreased after treatment. Conclusion： Fufangzhenwu Electuary was superior to independent conventional therapy in excessive neuroendocrine activation and inflammation course in CHF patients.
出处
《中国中医急症》
2010年第3期365-366,368,共3页
Journal of Emergency in Traditional Chinese Medicine
基金
安徽省科技计划项目(No.08020303064)
关键词
慢性充血性心力衰竭
心钠肽
超敏C反应蛋白
复方真武冲剂
中医证候
Chronic congestive heart failure
Atrial natriuretic peptide
High sensitivity C-reactive protein
Fufangzhenwu Electuary
Traditional Chinese medicine syndrome
