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慢性阻塞性肺疾病急性加重期证候及特征的临床调查研究 被引量:72

Clinical investigation of syndrome and characteristic of COPD in acute exacerbation stage
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摘要 目的:探讨慢性阻塞性肺疾病(COPD)急性加重期常见证候及其特征。方法:收集4所三甲医院COPD急性加重期患者资料,使用Epidata软件建立数据库,运用SPSS 13.0 for windows统计软件包进行频次和频率的统计描述及Logistic回归方法分析。结果:1046例患者中出现了28个证候,其中频率与构成比最高的证候是痰热壅肺证,分别为60.23%、8.77%,其次是肺气虚证,分别为46.18%、6.73%。COPD急性加重期常见证候有痰热壅肺证、外寒内饮证、痰湿阻肺证、痰瘀阻肺证、肺脾气虚证、肺肾气虚证、肺肾阴虚证、肺肾气阴两虚证,并对其主次症特征作了分析。结论:COPD急性加重期常见证候有8种,其中痰热壅肺证是最常见的一种。 Objective: To probe the common syndromes and characteristic of chronic obstructive pulmonary disease (COPD) at acute exacerbation stage. Methods: The hospitalized and out patients document of COPD at acute exacerbation stage were collected from 4 hospitals and the clinical research database was constructed. SPSS for windows ver.13.0 software was adopted for statistical description and Logistic regression. Results: There were 28 syndromes in 1 046 patients. Frequency and constituent ratio of syndrome of heat-phlegm stagnating the lung were the topmost (percent 60.2 and percent 8.77), then syndrome of insufficiency of lung qi (percent 46.2 and percent 6.73), while them of lowest were yang deficiency of the heart, spleen and kidney (percent 5.5 and percent 0.80). The common syndromes of COPD at acute exacerbation stage were syndrome of exogenous cold-evil and internal fluid retention, syndrome of heat-phlegm stagnating the lung, ~yndrome of pulmonary stagnation of phlegm, syndrome of retention of phlegm and blood stasis in the lung, syndrome of qi deficiency of the lung and kidney, syndrome of asthenia of pulmonosplenic qi, syndrome of lung-kidney yin deficiency, syndrome of qi-yin asthenia of the lung and kidney. Conclusion: There were 8 common syndromes of COPD at acute exacerbation stage. Syndrome of heat-phlegm stagnating the lung was the most common syndrome.
出处 《中华中医药杂志》 CAS CSCD 北大核心 2010年第4期504-509,共6页 China Journal of Traditional Chinese Medicine and Pharmacy
基金 国家自然科学基金资助项目(No.30772797) 河南省高校新世纪优秀人才支持计划(No.2006HANCET-05)~~
关键词 慢性阻塞.胜肺疾病 急性加重期 证候 Chronic obstructive pulmonary disease (COPD) Acute exacerbation stage Syndrome
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