期刊文献+

登革病毒E蛋白入胞机制研究现状 被引量:4

原文传递
导出
摘要 登革病毒(dengue virus,DENV)属于黄病毒科黄病毒属,是具有包膜的单股正链RNA病毒。病毒可通过埃及伊蚊和白纹伊蚊传播,引起登革热和登革休克综合征,广泛流行于热带和亚热带地区,全球流行超过100个国家。登革病毒依赖包膜蛋白E蛋白构象的改变,从而发生病毒包膜和宿主细胞膜之间的融合将病毒核酸传递入细胞质中,但其感染入胞机理尚不十分清楚。本文就登革病毒相关E蛋白入胞机制的最新研究进展作一简要综述。
出处 《热带医学杂志》 CAS 2010年第2期221-222,共2页 Journal of Tropical Medicine
基金 国家自然科学基金(No.30872216)
  • 相关文献

参考文献16

  • 1Leyssen P, De Clercq E, Neyts J.Perspectives for the treatment of infections with Flavivuridea [J].Clin Microbiol Rev,2000, 13(1):67-82. 被引量:1
  • 2Twiddy SS, Holmes EC, Rambaut A. Inferring the rate and time-scde of dengue virus evolution [J] .Mol Biol Evol, 2003, 20( 1 ) : 122-129. 被引量:1
  • 3Salas-Benito JS,del Angel RM.Identification of two surface proteins from C6/36 cells that bind dengue type g virus[J]. J Vfrol, 1997,71 (10) : 7246-7252. 被引量:1
  • 4Modis Y, Ogata S, Clements D, et al. A ligand binding pocket in the dengue virus envelope glycoprotein [J].Proc Natl Acad Sci USA, 2003,100(12) : 6986-6991. 被引量:1
  • 5Chen Y, Maguire T, Hileman ER, et al.Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate [ J ]. Nat Med, 1997,3 ( 8 ) : 866-871. 被引量:1
  • 6Modis Y,Ogata S,Clements D,et al.Structure of the dengue virus envelope protein after membrane fusion [ J ].Nature, 2004, 427(6972) : 313-319. 被引量:1
  • 7Bressanelli S, Stiasny K, Allison SL, et al. Structure of a flavivirus envelope glycoprotein in its low-pH-induced membrane fusion confonnation [J]. EMBO J,2004,23(4): 728-738. 被引量:1
  • 8Zhang Y, Zhang W, Ogata S, et al. Conformational changes of the flavivirus E glycoprotein [J].Structure,2004,12 (9): 1607-1618. 被引量:1
  • 9Modis Y,Ogata S,Clements D,et al.Variable surface epitopes in the crystal structure of dengue virus type 3 envelope glycoprotein [J]. J Virol, 2005,79(2):1223-1231. 被引量:1
  • 10Nayak V, Dessau M, Kueera K, et al. Crystal structure of dengue virus type 1 envelope protein in the postfusion conformation and its implications for membrane fusion [J]. J Virol, 2009,83 (9) : 4338-4344. 被引量:1

同被引文献59

  • 1朱武洋,秦鄂德.黄病毒衣壳蛋白研究进展[J].国际病毒学杂志,2006,13(2):47-50. 被引量:6
  • 2邓永强,秦鄂德.虫媒黄病毒包膜E蛋白的研究进展[J].军事医学科学院院刊,2006,30(6):575-579. 被引量:20
  • 3Brandler S,Ruffle C,Najburg V,et al.Pediatric measles vaccine expressing a dengue tetravalent antigen elicits neutralizing antibodies against all four dengue viruses[J].Vaccine,2010,28(41):6730-6739. 被引量:1
  • 4Block OK,Rodrigo WW,Quinn M,et al.A tetravalent recombinant dengue domain Ⅲ protein vaccine stimulates neutralizing and enhancing antibodies in mice[J].Vaccine,2010,28(51):8085-8094. 被引量:1
  • 5Guzman MG,Hermida L,Beruardo L,et al.Domain Ⅲ of the envelope protein as a dengue vaccine target[J].Expert Rev Vaccines,2010,9 (2):137-147. 被引量:1
  • 6Ooi EE,Goh KT,Chee WD.Effect of increasing age on the trend of dengue and dengue hemorrhagic fever in Singapore[J].Int J Infect Dis,2003,7 (3):231-232. 被引量:1
  • 7Guzman MG,Halstead SB,Artsob H,et al.Dengue:a continuing global threat[J].Nat Rev Microbiol,2010,8(12Suppl):S7-16. 被引量:1
  • 8Whitehead SS,Blaney JE,Durbin AP,et al.Prospects for a dengue virus vaccine[J].Nat Rev Microbiol,2007,5(7):518-528. 被引量:1
  • 9Gonzalez D,Castro OE,Kouri G,et al.Classical dengue hemorrhagic fever resulting from two dengue infections spaced 20years or more apart:Havana,Dengue 3 epidemic,2001-2002[J].Int J Infect Dis,2005,9(5):280-285. 被引量:1
  • 10Hombach J,Cardosa M J,Sabchareon A,et al.Scientific consultation on immunological correlates of protection induced by dengue vaccines report from a meeting held at the World Health Organization 17-18 November 2005[J].Vaccine,2007,25(21):4130-4139. 被引量:1

引证文献4

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部