摘要
目的观察布托啡诺超前镇痛用于显微支撑喉镜下成人声带息肉摘除术镇痛效果及安全性。方法择期行声带息肉摘除术患者40例,随机分为布托啡诺组(A组,n=20)和对照组(B组,n=20)。A组于麻醉诱导前5 min缓慢静注布托啡诺1.0 mg(用生理盐水稀释至5.0 mL);B组以生理盐水5.0 mL缓慢静注,观察术后1、2、4、8、12、24 h疼痛评分;呼吸抑制及头晕、恶心、呕吐等不良反应。结果A组术后各时间点疼痛评分明显低于B组(P<0.05),两组各时间点均无呼吸抑制发生,两组术后头晕、恶心、呕吐等不良反应发生率,差异无统计学意义(P>0.05)。结论布托诺啡超前镇痛能有效减轻显微支撑喉镜下行成人声带息肉摘除术患者术后的急性疼痛,而且无明显不良反应,可安全用于术后镇痛。
Objective To study effect and safety of butorphanol preemptive analgesia applying in adult vocal cord polyp excision by micro-suspension laryngoscope.Methods 40 cases of such patients were randomly divided into butorphanol group（A group,n=20） and control group（B group,n=20）.Group A was given10 mg slow intravenous butorphanol（diluted with saline to 50 mL） when 50 minutes before induction of anesthesia;Group B was given 50 mL saline Pain score;respiratory depression,and dizziness,nausea,vomiting and other adverse reactions was observed when 1,2,4,8,12,24 h postoperation.Results Pain score at each time point post operation in group A was significantly lower than group B（P〈0.05）,Two groups at all time points were no respiratory depression occurred.after two groups of The incidence of adverse reactions such as dizziness,nausea,vomiting,etc.was no statistically difference between two groups（P〉0.05）.Conclusion Butorphanol preemptive analgesia might reduce acute postoperative pain induced by the micro-suspension laryngoscope effectively after adult vocal cord polyp resection.The method has no significant side effects and it might be applied postoperative analgesia safety.
出处
《黑龙江医学》
2010年第2期123-125,共3页
Heilongjiang Medical Journal
关键词
布托啡诺注射液
超前镇痛
喉镜
声带息肉
术后镇痛
Butorphanol Injection
Preemptive Analgesia
Laryngoscopy
Vocal Cord Polyps
Postoperative Analgesia
