摘要
目的:比较左、右耳记录的言语诱发听性脑干反应(speech-ABR)在时域及频域上的差异,探讨脑干编码不同耳别来源的言语信息的差异及其可能原因。方法:以合成言语/da/为刺激声对健康成人进行双耳同侧记录的speech-ABR测试,分析反应的潜伏期、幅值及波形评分。对反应20～50ms部分进行快速傅立叶变换,计算基频及第一共振峰的幅值。结果:不同耳别记录的speech-ABR主波的潜伏期差异无统计学意义;右耳记录的A波幅值显著大于左耳记录,O波幅值则显著小于左耳记录,其他主波幅值的耳别差异均无统计学意义。右耳记录的波形评分大于左耳记录,两者差异有统计学意义。无论记录耳别,基频的幅值均大于第一共振峰的幅值,差异有统计学意义;无论是基频的幅值还是第一共振峰的幅值,耳别差异均无统计学意义。结论:speech-ABR在脑干的来源和分布无明显偏向性,与大脑半球言语功能的不对称性无明显对应性。听觉传导通路、功能性what-where通路以及大脑两侧半球不是简单的对应关系。
Objective：To compare the time domain and the frequency domain of speech-evoked auditory brainstem response measured by stimulation of left and right ears,and to explore the difference and possible reasons of neural coding for speech from different ears in auditory brainstem.Method：Speech-ABRs to syllable /da/ of 31 healthy adults were recorded. Statistical analysis was performed on time-domain parameters,such as latencies and amplitudes of featured peaks,and frequency-domain ones,such as amplitudes of the fundamental frequency and the first formant of speech-ABRs ranging from 20-50 ms. A scoring criterion to grade the appearance of featured waves was proposed for waveform evaluation.Result：There were no significant difference for the latencies of binaural featured peaks and amplitudes of feature peaks（except peaks A and O）. The waveform scores of right ear were greater than that of left ear. The amplitudes of fundamental frequency of binaural waves were both greater than that of the first formant. There was no significant difference of amplitudes of fundamental frequency and the first formant between two ears.Conclusion：The origins and distributions of speech-ABR are essentially symmetrical in brainstem in contrast with the hemisphere asymmetry of speech.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
CSCD
北大核心
2010年第4期161-165,共5页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
基金
国家自然科学基金(No:60771035)
关键词
同侧记录
双耳
言语
听性脑干反应
ipsilateral recording
bilateral ears
speech syllable
auditory brainstem response
