摘要
1例42岁女性患者,因右侧乳腺癌根治术后给予他莫昔芬10mg,1次/d长期维持治疗。后因高血压病加用厄贝沙坦150mg,1次/d。1个月后患者出现左侧颈部、腋下淋巴结及左侧乳房疼痛,经检查排除乳腺癌转移。考虑上述症状与厄贝沙坦有关,立即停用厄贝沙坦,继续使用他莫昔芬,1周后症状消失。之后,用氨氯地平和美托洛尔控制血压,上述症状未再发生。
A 42-year-old woman received tamoxifen 10 mg once daily for long-term maintenance therapy after undergoing mammary cancer radical operation.Irbesartan 150 mg once daily was added to her regimen due to hypertension.One month later,the patient developed painful left cervical and axillary lymph nodes and left breast.Mammary cancer metastasis was excluded.The above-mentioned symptoms were considered to be irbesartan-associated.Irbesartan was stopped and tamoxifen was continued.One week later,his symptoms disappeared.Subsequently,amlodipine and metoprolol were used for control of blood pressure and the above-mentioned symptoms did not recur.
出处
《药物不良反应杂志》
2010年第1期44-44,52,共2页
Adverse Drug Reactions Journal
关键词
厄贝沙坦
不良反应
乳房疼痛
淋巴结疼痛
irbesartan
adverse reactions
painful breast
painful lymph nodes
