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妊娠期糖尿病患者的脂代谢与新生儿出生体重的关系 被引量:4

Relationship between lipid metabolism of patients with gestational diabetes mellitus and neonatal birth weight
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摘要 目的:评价妊娠期糖尿病患者妊娠晚期血脂含量与新生儿出生体重之间的关系。方法:选择2006年10月~2009年10月宁波市象山县丹城中心卫生院收治的妊娠期糖尿病患者92例,并以242例同期正常孕妇为对照,采用酶法测定妊娠期糖尿病组孕妇和正常组孕妇的体内血脂水平。测定的血脂种类包括:血清甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL)及高密度脂蛋白(HDL),并对妊娠期糖尿病产妇血脂含量与新生儿体重关系进行分析。结果:与正常组相比,妊娠期糖尿病组孕妇脐带血清含量显著增高(P<0.05);妊娠期糖尿病组TC水平、LDL水平及HDL水平高于正常组,但差异无统计学意义(P>0.05),仅TG水平显著高于正常组(P<0.05)。Person’s分析显示,TG水平与新生儿体重间存在显著的正相关性(P<0.05)。结论:妊娠期糖尿病孕妇血清甘油三酯水平的增加与新生儿体重间存在较为密切的相关性。 Objective: To evaluate the relationship between blood lipids levels of patients in late pregnancy with gestational diabetes mellitus and neonatal birth weight. Methods: The blood lipids levels of 92 cases with gestational diabetes mellitus (diabetes group) and 242 normal pregnant women (control group) were detected by enzymic method from October 2006 to October 2009. The kinds of blood lipids included serum triglyceride ( TG), total cholesterol ( TC ), low - density lipoprotein (LDL) and high - density lipoprotein ( HDL), the relationship between blood lipids levels of patients in late pregnancy with gestational diabetes mellitus and neonatal birth weight was analyzed. Results: The levels of serum TC, LDL and HDL in diabetes group were higher than those in control group, but there was no significant difference ( P 〉 0. 05 ) ; the level of TG in diabetes group was significantly higher than that in control group ( P 〈 0. 05 ) ; Person' s a- nalysis indicated that there was a positive correlation between serum TG level and neonatal body weight ( P 〈 0.05 ) . Conclusion: There is a correlation between increase of serum TG in patients with gestational diabetes mellitus and neonatal birth weight.
作者 洪楚 袁亚仙
出处 《中国妇幼保健》 CAS 北大核心 2010年第9期1188-1189,共2页 Maternal and Child Health Care of China
关键词 妊娠期糖尿病 脂代谢 新生儿体重 Gestational diabetes mellitus Lipid metabolism Neonatal birth weight
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