摘要
提出了在Ｎ，Ｎ－二甲基甲酸胺（ＤＭＦ）存在下，用二氯乙烷萃取盐酸布比卡因与钴硫氰酸根生成的离子对缔合物，经反萃取后，用原子吸收光谱法测定反萃取液中的Ｃｏ２＋量间接确定盐酸布比卡因含量的新方法。本法在 ０．０５～１．３０ ｇ／Ｌ范围内呈良好线性关系（ｒ ＝０．９９９９），回收率在９８％～１０３％范围内。用于实际样品测定获得良好效果。
Ionic associate compound formed by bupivacaine hydrochloride with cobalt thiocyanate in the presence of N, N-dimethylformamide (DMF) was extracted by l,2-Dichloroethane. After stripping, a new atomic absorption spectrometry for the indirect determination of bupivacaine hydrocholride was established by measuring the Co2+ in water phase. The results show that in the range of 0 .05 - 1. 30 g/L, the method gives recovery of 98% - 103%. It has been applied to determine the content of bupivacaine hydrochloride in the sample and satisfactory results were obtained.
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
1998年第9期1105-1107,共3页
Chinese Journal of Analytical Chemistry
关键词
盐酸布比卡因
原子吸收光谱
反萃取
DMF
测定
Bupivacaine hydrochloride, atomicabosorption spectrometry, N, N-dimethyformamide, stripping
