摘要
目的比较米氮平与阿米替林治疗抑郁症的疗效和不良反应。方法应用米氮平和阿米替林治疗抑郁症各30例,应用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)进行评定,并进行临床疗效比较。结果米氮平与阿米替林治疗后HAMD、HAMA分值均显著下降,两组间减分比较,差异无显著性,米氮平不良反应发生率明显少于阿米替林。结论米氮平治疗抑郁症疗效与阿米替林相当,前者不良反应较轻,值得推广。
Objective To compare the curative effect and the side effect of mirtazapine and amitriptyline in treating depression. Methods 60 cases with depression were divided into 2 groups ： mirtazapine group and amitriptyline group, 30 cases in each ; HAMD Scale and HAMA Scale were applied in evaluation and curative effect comparison. Results The scores of HAMD and HAMA in both groups decreased significantly with no obvious difference while the occurrence of side effect in mirtazapine group was much lower than that in amitriptyline group. Conclusions Mirtazapine and amitriptyline have the same effect in treating depression; mirtazapine cuases slight side effect and is worthy of wide application.
出处
《西南军医》
2010年第2期238-239,共2页
Journal of Military Surgeon in Southwest China
关键词
抑郁症
米氮平
阿米替林
depression mirtazapine amitriptyline
