摘要
目的探讨纤维束示踪成像技术定量分析皮质脊髓束(CST)损伤对脑出血后运动功能结果的预测价值。方法对25例累及基底节区、内囊或者放射冠区等急性期脑出血患者行磁共振扩散张量成像(DTI)检查,应用日本东京大学VolumeOne1.64和diffusion Tensor VisualizerII(dTVII)软件进行白质纤维束的三维重建,通过感兴趣区(ROI)的设置得到患侧CST三维示踪图像,并由软件计算获得患侧相对剩余CST条目数。对脑出血患者6个月后运动功能评价采用Fugl-Meyer评分。结果25例患者的患侧相对剩余CST条目数与6个月后Fugl-Meyer评分之间具有较高的相关性(r=0.879,P<0.01)。结论利用纤维束示踪成像技术对皮质脊髓束的定量分析可以早期对脑出血患者运动功能结果进行预测评估。
Objective: To investigate the predicting value by analyzing corticospinal tract (CST) injury to the motor function after intracerebral hemorrhage (ICH) with quantitative diffusion tensor tractography (DTT). Materials and Methods: Diffusion tensor imaging was performed in twenty-five acute ICH patients, whose hemorrhage involves basal ganglia, internal capsule or corona radiate. The affected side of CST was reconstructed with Volume-One 1.64 and diffusion Tensor Visualizer II(dTV II) software from Tokyo University. The relative remaining number of CST, which is as quantitative indicator, was calculated. Fugl-Meyer scoring was used to evaluate the prognosis. Results: The correlation coefficient (r value) between relative remaining number of CST and Fugl-Meyer score after six month of ICH is 0.879 (P〈0.01). Conclusion: Quantitative DTT of CST could be used to predict the motor function in ICH patients.
出处
《磁共振成像》
CAS
2010年第1期15-18,共4页
Chinese Journal of Magnetic Resonance Imaging
基金
江苏省卫生厅医学科技发展基金资助(H200356)
关键词
纤维束示踪成像技术
磁共振成像
运动皮质
脑出血
Diffusion tensor tractography
Magnetic resonance imaging
Motor cortex
Cerebral hemorrhage