摘要
目的:评价采用无缝线粘贴法应用于翼状胬肉手术的疗效。方法:对57例75眼鼻侧原发性翼状胬肉患者,随机分成4组,A、B组为新方法无缝线粘贴法,粘合剂为生物粘合剂纤维蛋白粘合剂,其中A组13例(16眼)采用逆向翼状胬肉切除+角膜缘干细胞移植,结膜瓣采用纤维蛋白粘合剂粘贴。B组12例(15眼)组采用逆向翼状胬肉切除+生物羊膜移植,生物羊膜采用纤维蛋白粘合剂粘贴。C、D组为常规缝合组,其中C组13例(18眼)采用逆向翼状胬肉切除+生物羊膜移植,生物羊膜采用10-0尼龙线缝合。D组19例(26眼)采用逆向翼状胬肉切除+角膜缘干细胞移植,结膜瓣采用10-0尼龙线缝合。对手术时间、疼痛感觉、复发率、并发症等指标进行比较分析。结果:手术时间:A组与B组比较无显著性差异(P>0.05);A组与C组、D组;B组与C组、D组比较具有显著差异性(P<0.05)。C组与D组无显著差异性(P>0.05)。疼痛评估:A、B组比较无显著性差异(P>0.05),A组与C组、D组;B组与C组、D组具有显著差异性(P<0.05);C组与D组无显著差异性(P>0.05)。A组16眼术后复发1眼,复发率为6.3%;B组15眼术后复发2眼,复发率为13.3%;C组18眼术后复发3眼,复发率为16.7%;D组26眼术后复发2眼,复发率为7.7%;各组间无显著差异性。结论:在翼状胬肉手术中,采用逆向翼状胬肉切除+角膜缘干细胞移植,结膜瓣采用纤维蛋白粘合剂粘贴,可减轻患者疼痛,减轻炎症反应,缩短手术时间,提高手术质量,降低复发率。
Objective： To observe the therapeutic effects in treatment of pyerygium of no suture paste. Method ： Retrospective study The study included 75 eyes of 57 patients operated for primary nasal pterygium between 2007/9 and 2009 /6 and followed for≥3 months, randomly divided into four groups： group A and group B used new method of no suture paste ： bond use biotic bond of fibrin tissue adhesive, reversectomy of pterygium with Limbal stem cells graft autograft with conntive-conjunetive transplantation （group A, 16 eyes） ： conntive-eonjtmetive paste use fibrin tissue adhesive;reverseetomy of pterygium with biotic amniotic membrane transplantation （group B, 15 eyes） ; biotic amniotic membrane paste used fibrin tissue adhesive, group C and group D used usually method of suture ： reverseetomy of pterygium with biotic amniotie membrane transplantation （group C, 18 eyes） ; biotic amniotie membrane suture use 104） nylon suture, reversectomy of pterygium with Limbal stem cells graft autograft with eonntive-eonjunetive transplantation （group D, 26 eyes） ： conntive-conjunctive suture use 104） nylon suture; Main outcome measures：average surgery time, average pain, recurrence rate and complications. Result： The average surgery time： The differences were not statisticallly significant between the group A and B（ P 〉 0.05 ） ; The differences were statisticallly significant between the A and group C ,D（P 〈0.05） ; The differences were statisticaltly significant between group B and C ,D（ P 〈 0.05 ） ; The differences were not statistical significant between group C and D （ P 〉 0.05 ）. The average paini The differences were not statistical significant between group A and B （ P 〉 0.05 ） ; The differences were statistical significant between group A and C, D （ P 〈 0.05 ） ; The differences were statistical significant between group B and C ,D（ P 〈 0.05 ） ; The differences were not statistical significant between group C and D（P 〉0.05 ）. The recurrence r
出处
《赣南医学院学报》
2010年第1期29-32,共4页
JOURNAL OF GANNAN MEDICAL UNIVERSITY
基金
韶关市2008年立项课题 韶科(卫)2008-10
关键词
翼状胬肉
纤维蛋白粘合剂
逆向切除
角膜缘干细胞
移植
羊膜
Pterygium
fibrin tissue adhesive
reversectomy
Limbal stem cells graft
Transplantation
Biotic amniotic membrane
