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参脉注射液对急性病毒性心肌炎患儿血清中MIF和TNF-α的影响及意义 被引量:4

Effects of Shenmai injection on serum migration inhibitory factor and tumor necrosis factor-α levels in patients with aute viral myocarditis and its significance
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摘要 目的:观察参脉注射液对急性病毒性心肌炎患儿血清中巨噬细胞移动抑制因子和肿瘤坏死因子-α的影响及意义。方法:60例急性病毒性心肌炎患儿随机分为两组。常规组采用常规治疗,治疗组在常规组的基础上联合参脉注射液治疗。评价两组患儿有效率。检测患儿治疗前后血清中巨噬细胞移动抑制因子和肿瘤坏死因子-α浓度。结果:治疗组有效率明显高于常规组,血清中巨噬细胞移动抑制因子和肿瘤坏死因子-α浓度低于常规组,差异均有显著性。结论:参脉注射液可能通过下调急性病毒性心肌炎患儿血清中巨噬细胞移动抑制因子和肿瘤坏死因子-α浓度,抑制炎症反应,提高急性病毒性心肌炎患儿治疗效果,值得临床推广。 Objective To study effection of Shenmai injection on serum migration inhibitory factor and tumor necrosis factor -α levels in patients with aute viral myocarditis and its significance. Method 60 cases of ante viral myocarditis were randomly divided into two groups. Conventional group were treated with conventional therapy, the treatment group in the conventional group on the basis jointed Shenmai injection, the efficiency of two groups of patients were appraised, before and after treatment in patients with serum macrophage migration inhibitory factor and tumor necrosis factor -α were tested. Result Efficient of the treatment group were significantly higher than those of the conventional group. Serum macrophage migration inhibitory factor and tumor necrosis factor -α concentration were lower than those of the conventional groups the differences were significant. Conclusion Shenmai injection could be by down - regulation in children with ante viral myocarditis in patients with serum macrophage migration inhibitory factor and tumor necrosis factor-α concentrations, inhibit inflammatory response, improve treatment of viral myocarditis in children and worthy to be popularized.
作者 方清
出处 《中国民族民间医药》 2010年第5期31-32,共2页 Chinese Journal of Ethnomedicine and Ethnopharmacy
关键词 参脉注射液 急性病毒性心肌炎 肿瘤坏死因子-α 巨噬细胞移动抑制因子 Shenmai injection aute viral myocarditis tumor necrosis factor -α macrophage migration inhibitory factor
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