摘要
目的:对比分析3种不同用药方案治疗消化性溃疡的最小成本。方法:选择性地将无其他并发症的960例消化性溃疡患者随机分为A组(奥美拉唑肠溶片+克拉霉素胶囊+复方氢氧化铝片)、B组(奥美拉唑肠溶片+枸橼酸铋钾颗粒+雷尼替丁胶囊)、C组(兰索拉唑片+胶体果胶铋胶囊+阿莫西林胶囊),运用药物经济学方法进行回顾性分析。结果:A、B、C3组有效率分别为85.93%、88.44%、89.38%,成本分别为589.96、539.00、284.34元。3组病例中,都有个别病例出现比较轻微的头痛、恶心、嗜睡、便秘等不良反应,没有对症治疗,有的病例进行了膳食调节,疗程结束后自行恢复。结论:3组疗效比较无显著性差异(P>0.05),C组治疗方案成本最低,最为经济。
OBJECTIVE： To compare and analyze the minimum cost of three kinds of different drugs in the treatment of peptic ulcer. METHODS： 960 cases of peptic ulcer patients without other complications were randomly divided into group A （Omeprazole Magnesium Enericcoated Tablets＋Clarithromycin Capsules＋Compound Aluminium Hydroxide Tablets）, group B（Omeprazole Magnesium Enericcoated Tablets＋Bismuth Potassium Granules＋Ranitidine Hydrochloride Capsules）, group C （Lansoprazole Tablets＋ Colloidal Bismuth Pectin Capsules＋Amoxicilin Capsules）. Using economic methods to analyzed retrospectively. RESULTS： Effective rate of A, B, C 3 group were respectively 85.93%, 88.44%, 89.38%, costs were 589.96, 539.00, 284.34 yuan. In 3 groups, there were individual cases was relatively minor headache, nausea, drowsiness, constipation and other adverse reactions; there was no symptomatic treatment; some patients had dietary regulation and self-healing after treatment. CONCLUSION： Compared with the other two groups, there are no significant differences in efficacy in three groups （P〉0.05） ; group C is the lowest-cost treatment options and the most economical one.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第8期760-761,共2页
China Pharmacy
