摘要
目的:探讨联合应用降压药治疗2型糖尿病合并高血压临床疗效。方法:采取随机分组平行分组对照方法,将患者分为两组,A组29例,单用硝苯地平缓释片40 mg/d;B组29例,硝苯地平缓释片20 mg/d+缬沙坦(血管紧张素Ⅱ受体阻滞剂,ARB)80 mg/d。结果:治疗8周后,B组收缩压(SBP)<130 mm Hg和舒张压(DBP)<80 mm Hg,达标率分别为68.96%和93.10%,较A组明显增高(P<0.05),不良反应少(P<0.05)。结论:钙拮抗剂联合ARB治疗2型糖尿病合并高血压疗效理想,且不良反应低。
Objective：To explore the clinical effects of combination depressurization therapy in patients with type 2 diabetes combined with hypertension. Methods：The patients were divided into two groups （ A and B） by random allocation and parallel-group control method. The patients in group A received nifedipine sustained-- released tablets 40 mg/d single,and the patients in group B received nifedipine sustained-released tablets 20 mg/d and valsartan（ARB）80 mg/d. Results： After treatment for 8 weeks, SBP〈130 mm Hg and DBP〈80 mm Hg of patients in group B. The normal rates of SBP and DBP of patients were 68.96% and 93.10% respectively. There was a significantly increases in group B than group A（ P〈0.05）, and there was a less adverse reaction in group B（ P〈0.05 ）. Conclusions：There is an ideal curative effects and a less adverse reactionin treatment of type 2 diabetes combined with hypertension with ARB.
出处
《中国误诊学杂志》
CAS
2010年第7期1531-1532,共2页
Chinese Journal of Misdiagnostics
