摘要
目的观察甲磺酸罗哌卡因单次硬膜外腔注射用于妇产科手术后镇痛的临床效果。方法180冽妇产科手术患者随机分为两组：治疗组在手术缝皮肤时通过硬膜外腔一次注射镇痛液（罗哌卡因＋吗啡），对照组在手术缝皮肤时注入镇痛液5～6ml后接自控式镇痛泵，观察两组血流动力学、心率变化情况及术后48h镇痛效果、不良反发生率等。结果两组镇痛前后平均动脉压、血氧饱和度、心率比较，差异无统计学意义（均P〉0．05）；治疗组术后24h、48h镇痛效果0级（无痛率）均明显高于对照组（χ2=3．9．74、4．031，均P〈0．05）；两组未发生严重不良反应。结论甲磺酸罗哌卡因单次硬膜外腔注射用于妇产科术后镇痛效果好、不良反应少。
Objective To observe the clinical effect of using single epidural injection of S-Ropivacaine Mesylate to ease the pain after gynaecology and obstetrics operations. Methods 180 patients who need gynaecological operations were randomly divided into two groups. The group of therapy was injected the analgesic（ ropivacaine ＋ mor- phia） at once when suturing the skin. And the comparing group only injected 5 ~ 6ml of analgesic at the stage of skin suture, then selfoperated analgesia pump will be used. The changes of hemodynamics and SpO2 of tile two groups, the analgesic activities after 48 hours, occurrence of adverse reaction, etc were analyzed. Results The differences of MAP,SpO2 ,and HR had statistical significance（P 〉 0. 05） ;After the surgery, the effect of analgesic of 24h and 48h grade 0（ pain-free rate） in therapy group is much more obvious than comparing group（ χ2 = 3. 974,4. 031 ,P 〈 0. 05 ） ; Neither group has severe adverse reaction. Conclusion The effect of using sihgle epidural injection of S-Ropivacaine Mesylate to ease the pain after gynaecology and obstetrics surgeries is good, and has little adverse reaction.
出处
《中国基层医药》
CAS
2010年第2期156-157,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
镇痛
产科
妇科外科手术
甲磺酸罗哌卡因
Analgesia, obstetrical
Gynecologic surgical procedures
Ropivacaine
