摘要
目的比较华法令与阿司匹林对老年房颤患者脑栓塞的预防作用和疗效。方法将91例老年房颤患者分为阿司匹林抗栓组及华法令抗栓组,同时对华法令抗栓组检测INR,根据INR调整华法令的剂量。结果随访3年阿司匹林抗栓组及华法令抗栓组脑栓塞的发病率为12.5%,2.0%,阿司匹林抗栓组脑栓塞的发病率明显高于华法令抗栓组,差异有显著性(P<0.05);出血发病率:阿司匹林抗栓组及华法令抗栓组的发病率为2.5%,5.9%,差异无显著性(P>0.05)。结论对老年房颤患者使用华法令,严格检测INR在2.0～3.0是安全有效的。
Objective The purpose of this analysis was to compare warfarin and aspirin in elderly patients with atrial fibrillation in cerebral embolism and efficacy of the preventive effect.Methods 91 elderly patients with atrial fibrillation patients were divided into aspirin antithrombotic group and warfarin antithrombotic group,while warfarin group was testing antithrombotic INR,and according to INR adjusting the dose of warfarin.Results After 3-year follow-up,the incidence of cerebral embolism for aspirin antithrombotic group was 12.5%,and warfarin antithrombotic group was 2.0%.The incidence of cerebral embolism in aspirin antithrombotic group was significantly higher than that in warfarin antithrombotic group and the difference was significant,P〈0.05.The incidence of bleeding aspirin antithrombotic group was 2.5%,while which in the warfarin antithrombotic group was 5.9%,there is no significant difference P〉 0.05.Conclusions Using warfarin in the range of 2.0 to 3.0 with strict testing of INR in in elderly patients with atrial fibrillation was safe and effective.
出处
《基层医学论坛》
2010年第5期99-100,共2页
The Medical Forum
