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粒细胞刺激因子治疗急性骨髓性白血病的系统评价 被引量：1

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摘要 目的:评价粒细胞刺激因子(G-CSF)治疗急性骨髓性白血病(AML)的疗效。方法:计算机检索PubMed、EM-Base、Cochrane图书馆、CBM、CNKI数据库,手检其他白血病相关杂志,对纳入的随机对照试验(RCT)进行方法学质量评价,并用RevMan5.0软件进行Meta分析。结果:共纳入11个RCT,A、B、C级文章分别有3,5,3篇。合并分析结果显示完全缓解率(CR)、总有效率(OS)、复发、感染等组间差异均显著性。结论:基于目前临床研究结果G-CSF不能增加患者完全缓解率、总有效率,亦不能降低复发、感染。
作者 吴斌 徐珽 苏娜 程凯 胡海波 柳汝明 唐尧
机构地区 四川大学华西药学院 四川大学华西医院药剂科
出处 《中国医院药学杂志》 CAS CSCD 北大核心 2010年第3期255-258,共4页 Chinese Journal of Hospital Pharmacy
关键词 粒细胞刺激因子 急性骨髓性白血病 系统评价
分类号 R979.1 [医药卫生—药品]
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参考文献12

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二级参考文献13

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中国医院药学杂志
2010年 第3期

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