摘要
目的探讨Askin瘤的临床、病理特征及预后。方法以"Askin瘤"为关键词,结合本院发现的1例,检索1980年1月至2009年6月中国生物医学文献数据库(CNKI)所有个案共35例,剔除病理分析报告及重复病例,进行临床、病理特点分析。结果Askin瘤多发于青少年胸肺区,常因胸痛或胸壁肿物求诊,易被误诊,易全身转移,免疫组化以CD99、NSE和S-100蛋白阳性为特征。结论Askin瘤罕见,高度恶性,目前多主张综合治疗,但疗效不佳。
Objective To study the clinical and pathological features and prognosis of Askin tumor. Methods Searching in China National Knowledge Infrastructure with keyword ＂Askin＂ from January 1980 to June 2009, all the reported cases including 1 described case had been analyzed on clinical pathology features, excluding repeated reported cases and pathological analysis articals. Resuits The tumor was often found in thoracopulmonary area of young patients, easily misdiagnosed and occurred distant metastasis, which chief complain was chest pain and（or） chest wall mass. The tumor cells were positive for CD99, NSE and S-100protein immunohistochemically. Conclusion Askin tumor is a rare and high malignant sarcoma. Comprehensive treatment is promoted, but the prognosis was quite dismal.
出处
《临床肿瘤学杂志》
CAS
2010年第2期166-168,共3页
Chinese Clinical Oncology
关键词
ASKIN瘤
临床病理
免疫组化
治疗
Askin tumor
Clinicopathology
Immunohistochemistry
Therapy
