摘要
目的探讨感染性心内膜炎(Infective endocarditis,IE)的临床特点及诊治方法。方法回顾性分析我院2006年1月至2009年6月收治的48例IE患者的临床资料。结果IE的主要临床表现仍为发热(93.7%)、心脏杂音(91.6%);血培养阳性率为39.6%,其中草绿色链球菌占36.8%,金黄色葡萄球菌占31.5%;IE中有器质性心脏病者占85.4%,其中风湿性心脏病占29.1%、先天性心脏病占18.7%,瓣膜退行性病变占14.5%;超声技术在心脏赘生物的检出率为83.33%;阳性率远高于血培养。结论近年来由于IE的流行病学有所变迁,IE的临床特征也有所变化;基础心脏病仍是IE常见病因;反复血培养和超声心动图检查可提高确诊率;规范、有效的抗生素治疗和合理的手术治疗可降低病死率。
Objective To analyze the clinical characteristics of infective endocarditis （IE） and then improve the diagnosis · and treatment of IE. Methods The clinical material of 48 patients with IE treated in our hospital from January 2006 to June 2009 were analyzed retrospectively. Results The major clinical manifestation is still fever （93.7%） and cardiac murmu （91.6%） ; the positive results in the blood culture is about 39.6%, and among them, viridans streptococcus accounting for 36.8%, and staphylococcus aureus accounting for 31.5%. 89. 7% patients had basic heart disease, including 29.1% of rheumatic heartdisease, 18.7% of congenital heart diseases, 14.5% of the valve degenerative disease. Vegetations were found in cases （83.33%） by echocardiography. Conclusion The onset age of infective endocarditis had increased evidently during the past years, and the risk factors of infective endocarditis had undergone significant diversification, and the major clinical feature changed. Blood cultures and echocardiography can confirm the early diagnosis. Early diagnosis and prompt treatment both medical and surgical interventions can improve the outcome of IE.
出处
《海南医学》
CAS
2010年第5期17-18,26,共3页
Hainan Medical Journal
