摘要
目的分析胃癌肝转移和无肝转移患者的临床病理因素,确立临床病理因素与胃癌肝转移的关系。方法回顾性分析2002～2008年收治的胃癌发生肝转移和非肝转移的患者各78例的临床病理资料,对胃癌肝转移的可能危险因素采用Logistic回归模型进行单因素和多因素分析。结果单因素分析结果显示胃癌的临床病理分期、大体类型、分化程度、浸润深度、脉管浸润、肿瘤直径和淋巴结转移与胃癌肝转移有关,通过Logistic回归模型多因素分析显示大体类型(P=0.003,OR=6.198)和脉管浸润(P=0.026,OR=2.571)是胃癌肝转移最重要的影响因素。结论胃癌发生肝转移可能与肿瘤的大体类型、脉管浸润、分化程度、肿瘤直径、淋巴结转移、浸润深度和临床病理分期有关。
Objective To analyze the clinical pathology factors of gastric tumor with and without hepatic metastasis. To assess the association between clinical pathology factors and hepatic metastasis of gastric tumor. Methods Retrospectly analyzed cases of gastric tumor includeing hepatic metastasis and without hepatic metastasis composed by Clinical data of 78 gastric carcinoma pa- tients collected in the first Affiliated Hospital of XinJiang Medical University. Analyzed the risk factors in hepatic metastasis of gas- tic carcinoma,and the correlation analysis including singular and multiple factors was conducted with logistic regression method. Re- sults As revealed by singular factor analysis, hepatic metastasis was related to ctinicopathologic stage, histological grade, tumor diferentiatio,Infiltration depth, canalis haemalis encroachment,turner diameter and lymph node metastasis was also a risk factor in hepatic metastasis according to singular factor analysis. By multiple factor analysis, Logistic regression showed histological grade（P =0. 003 ,OR=6. 198） and canalis haemalis encroachment（P=0. 026,OR=2. 571）were primary risk factors with hepatic metastasis from gastrc cancer. Conclusion Histological grade,tumor diferentiatio,canalis haemalis encroachment,turner diameter ,infiltration depth,lymph node metastasis and clinicopathologic stage of gastric carcinoma are risk factors related to hepatic metastasis.
出处
《重庆医学》
CAS
CSCD
北大核心
2010年第4期420-422,424,共4页
Chongqing medicine
基金
新疆维吾尔自治区自然科学基金项目(200821146)
