摘要
目的了解云南省正常人及主要家畜立克次体血清流行病学特点。方法按地理位置,选择云南省东北寻甸回族彝族自治县、西北玉龙纳西族自治县及南部的思茅地区3个调查点,以间接免疫荧光法检测莫氏立克次体、黑龙江立克次体、恙虫病东方体、贝氏柯克斯体、横赛巴尔通体、查菲埃立克体及人粒细胞无形体等8种常见立克次体血清IgG或IgM抗体。结果3个调查点237份成人,莫氏立克次体、巴尔通体及贝氏苛克斯体IgG抗体阳性率分别为16.46%、6.33%、9.28%。50岁人群最高(21.74%、9.57%及14.78%),而4-6岁儿童调查结果显示,莫氏立克次体IgG抗体阳性率最高,达12.35%(10/81),动物8种病原体抗体IgG及IgM抗体均检出,其中莫氏立克次体阳性率最高(61.48%),且地区间差异无显著意义。结论云南省正常农业人群及家畜存在多种立克次体感染,以莫氏立克次体、巴尔通体及贝氏柯克斯体为多。
To understand the sero-epidemiological features of rickettesiosis of humans and domestic animals in Yunnan province, blood samples from 237 adults in different geographic area, including Xundian country, Yulong country and Simao country and 81 children aged from 4 to 6 years old were collected for serological testing. In addition, 90 blood samples from dogs, goats and ox in each investigated area were also collected. Antibodies against 8 rickettsiae, including R. typhi, R. heilongjiangii or R. sibirica , Orientia tsutsugamushi Karp or Kato, Ehrlichia cha f f eensis , Ana plasma phagocytosis , Bartonella henselae, Coxiella burnetii and Hainan spotted fever group of rickettsia were examined by using immunofluorescence assays （IFA） o It was found that the sero-epidemiologic rates of R. typhi, B. henselae and C. burnetii （16.46% ,6.33% and 9.28%） of adults were higher than those of other rickerrsiae investigated. The positive rates of IgG antibody against R. typhi for children also shared the higher rate （12.35%）. Similar sero-epidemiologic features were found for domestic animals. Among the 8 rickettsia tested in this study, the positive rate of IgG antibody against R. typhi appeared to be the highest（61.48%） without significant difference among these investigated sites. From this investigation, it is evident that the rickettsial infection of farm population and domestic animals are common in Yunnan province, and the active surveillance of rickettsiosis and differential diagnosis of unknown febrile patients in clinical practice should be enforced.
出处
《中国人兽共患病学报》
CAS
CSCD
北大核心
2010年第2期189-192,F0003,共5页
Chinese Journal of Zoonoses
基金
中美新发传染病合作项目(1U2GGH000018-01)
国家基础研究项目-973计划2010CB530200(2010CB530206)
国家自然科学基金(30771854)联合资助
