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中低位直肠癌617例临床分析 被引量:1

Clinical Analysis on the Therapeutic Outcome of the Middle and Low Rectal Carcinoma : Report of 617 Cases
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摘要 为探讨中低位直肠癌根治术中保留盆腔自主神经(PANP)对男性排尿及性功能的影响.收集山东省立医院胃肠外科收治的617例男性直肠痛保肛手术患者的临床资料,按手术方式分为传统手术组(102例)、直肠全系膜切除术(TME)组(153例)和PANP+TME组(362例)。并对各组患者肿瘤下缘至肛门距离、3年生存率、局部复发率、排尿功能、性功能进行对比分析。结果显示.TME组和PANP+TME组的局部复发率较传统手术组明显降低(P〈0.05);传统手术组、TME组和PANP+TME纰的排尿障碍、勃起功能障碍及射精功能障碍的发生率均逐渐降低,三组间两两比较差异均有统计学意义(P〈0.05)。结果表明.PANP+TME可以降低直肠癌的局部复发率,降低排尿障碍和性功能障碍的发生率。 The ohjective of the study was to analyze the efficacy of pelvic autonomic nerve preservation (PANP) in the radical surgery of middle and low rectal carcinoma on the male's urination and sexual function. The clinical data of 617 male patients with rectal carcinoma who had undergone anus-preservation sur- gical procedure in gastrointestinal surgical department of shandong provincal hospital were collected. Ac- cording to the surgical procedures, these patients were divided into 3 groups: the traditional procedure group(TR group, n=102),the total mesorectal excision group(TME group, n=153) and the PANP+ TME group(n=362). The distance between lower tumor margin and anus, 3-year survival rate,local recurrence rate, urination function and sexual function in the 3 groups were taken as indexes in the analysis. As results,the local recurrence rate in the TME and PANP+TME groups were notably lower ( P 〈0.05) and the urinary dysfunction rate,erection dysfunction rate & ejaculation dysfunction rate in the 3 groups were all reduced,while there was statistical significance among the 3 groups( P 〈0.05). It is concluded that the procedure of PANP+TME can reduce the local recurrence rate of the rectal carcinomata,and reduce the incidence rate of urination dysfunction & sexual dysfunction.
作者 刘强
出处 《中国肛肠病杂志》 2009年第12期19-21,共3页 Chinese Journal of Coloproctology
关键词 直肠癌 保留盆腔自主神经 直肠全系膜切除术 疗效 Rectal carcinoma Pelvic autonomic nerve preservation Total mesorectal excision Therapeutical efficacy
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