摘要
目的观察血塞通软胶囊对颈动脉粥样硬化斑块中软斑块的临床疗效。方法将240例患者按随机数字表法分成两组各120例。对照组采用肠溶阿司匹林、辛伐他汀常规治疗；治疗组在对照组治疗基础上加用血塞通软胶囊，两组均治疗6个月为1个疗程，随访1年。结果两组治疗后软斑性质、数目、体积均较治疗前显著改善，且治疗组在软斑消退、软斑转为硬斑、软斑数目、软斑体积等方面优于对照组（t=3．525，P〈0.01）。治疗组心脑血管事件发生和再住院情况优于对照组（t=3．678，P〈0．01）。结论血塞通软胶囊可有效治疗颈动脉粥样硬化软斑块，降低心脑血管疾病事件的发生率。
Objective To observe the clinical effects of Xuesaitong Soft Capsule （XSC） on soft plaque in patients with cerebrovascular carotid atherosclerosis. Methods 240 patients with cerebrovascular carotid atherosclerosis were randomly recruited into two groups： 120 patients in a control group treated by conventional therapy （aspirin and simvastatin）, while the other 120 patients in a treatment group were treated by conventional therapy plus XSC. Both groups received the treatment for 6 months, followed by 1 year＇s succedent study. Results The nature, number and size of soft plaque were apparently improved after treatment in both groups. Such improvements as subsidence of soft plaques, soft plaque turning into a hard plaque, the number of soft plaque and soft plaque volume in the treatment group were superior to the control group （t= 3.525, 0.01）. Cardiovascular and cerebrovascular events and re-hospitalization in the treatment group were also lower than the control group （t=3.678, 0.01 ） .Conclusion XSC is effective in the treatment of carotid atherosclerosis soft plaque and significantly decrease the incidence of cardiovascular and ccrcbrovascular disease..
出处
《国际中医中药杂志》
2010年第1期20-21,共2页
International Journal of Traditional Chinese Medicine
关键词
颈动脉粥样硬化斑块
软斑
血塞通软胶囊
脑血管病
Carotid atherosclerosis
Soft plaque
Xuesaitong Soft Capsule
Cerebrovascular disease
