摘要
目的探讨血清高敏C反应蛋白（hs—CRP）及S100B蛋白水平与脑出血病情、出血量及预后的关系。方法对脑出血患者155例分型，用免疫透射比浊法测定hs—CRP含量，用双抗体夹心ELISA法测S100B蛋白含量，观察二者水平与脑出血病情、出血量及预后的关系。结果①脑出血病情愈重，血清hs—CRP及S100B蛋白含量愈高（P〈0．01）；②脑出血患者出血量愈多，hs—CRP及S100B蛋白含量愈高（P〈0．01）；③hs—CRP及S100B过高者，脑出血预后不良。④hs—CRP及S100B水平呈正相关（r=0．7，P=0．001）。结论hs—CRP及S100B水平是判断脑出血患者病情和预后的良好监测指标。
Objective To discuss the relationship between high sensitive - C reactive protein （hs- CRP） , S100B protein level and the intracerebral hemorrhage condition, hemorrhage amount and prognosis. Methods To type 155 patients＇intracerebral hemorrhage, and determine the content of hs - CRP by using immunoturbidimetrie and the content of S100B by ELISA. The relationship between their level and intraeerebral hemorrhage condition, hemorrhage amount and prognosis was observed. Results ①The more serious intraeerebral hemorrhage condition was, the higher the content of hs - CRP and S100B protein were （ P 〈0. 01 ）. ②The more hemorrhage amount was, the higher content of hs - CRP and S100B protein were （P 〈0. 01 ）. ③The prognosis of intracerebral hemorrhage patients with higher hs - CRP and S100B protein were not good. ④The level of hs - CRP and S100B protein were positive correlation （ r = 0.7 ,P = 0. 001 ）. Conclusion hs -CRP and S100B protein level are good indexes to judge the disease condition and prognosis of intracerebral hemorrhage patients.
出处
《中国急救医学》
CAS
CSCD
北大核心
2010年第1期61-64,共4页
Chinese Journal of Critical Care Medicine
