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超声弹性成像评估离体肝硬化标本结节性病变性质的初步研究 被引量:4

Primary study of real time elastosonography in estimating the characteristic of nodes in resected hepatocirrhosis specimens
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摘要 目的探讨实时超声弹性成像评估离体肝硬化标本结节性病变性质的可行性。方法选择38例肝移植受者新鲜离体肝标本,对感兴趣结节采用手动加压法进行实时超声弹性成像检查。感兴趣区域内肝实质本身的机械属性(应变)由彩色编码显示,将结节性病变的硬度与周围肝组织的硬度进行比较,将结节分为硬结节、中等硬度结节、软硬混合结节和软结节。所有结节均由病理明确诊断。结果对38例肝硬化标本的44个结节性病变进行了实时超声弹性成像检查。硬结节18个,其中12个(66.7%)为肝细胞肝癌,2个(11.1%)为不典型增生,4个(22.2%)为再生结节。中等硬度结节7个,均为再生结节。软硬混合结节11个,8个(72.7%)为肝细胞肝癌(其中4个伴有坏死组织),1个(9.1%)为不典型增生伴坏死组织,另2个(18.2%)为再生结节伴坏死组织。软结节8个,其中4个(50.0%)为坏死结节,1个为(12.5%)不典型增生伴部分癌变,1个(12.5%)为肝细胞肝癌,2个(25.0%)为再生结节。结论实时超声弹性成像可有效评估肝硬化标本结节性病变的相对硬度,可能在鉴别肝硬化结节性病变的性质方面具有潜在的用途。 Objective To evaluate the feasibility of real time elastosonography in estimating the characteristic of nodules in resected hepatocirrhosis specimens. Methods Thirty-eight resected hepatoeirrhosis specimens underwent elastosonography. The nodules that have drawn attention were performed elastosonography through rhythmic pressing and releasing the probe by manual form on the liver. The hepatic strain on the region of interest was shown by chromatic scale. To compare nodules rigidity with surrounding hepatic tissues, hepatocirrhosis nodules were classified into hard nodules, medium rigidity nodules, mixture of hard and soft nodules, and soft nodules. All nodules were confirmed by pathology. Results Forty-four nodules of 38 hepatocirrhosis exemplar received real time elastosonography. Of 44 nodules, hard nodules were 18, of which 12 (66.7%) were hepatocellular carcinomas, 2 ( 11. 1% ) were dysplasia nodules, 4 (22.2%) were regenerative nodules. Medium rigidity nodules were 7 ,all were regenerative nodules. Mixture of bard and soft nodules were 11, of which 8(72.7%) were hepatocellular carcinomas, including 4 accompanied necrotic tissue, 1 (9.1%) was dysplasia nodules accompanied necrotic tissue, the other 2 (18.2%) were regenerative nodules accompanied necrotic tissue. And soft nodules were 8, of which 4 (50.0%) were necrotic nodules, 1 (12.5 % ) was dysplasia nodules accompanied canceration, 1 ( 12.5 % ) was hepatocellular carcinoma, 2(25.0 % ) were regenerative nodules. Conclusions Real time elastosonography can effectively evaluate the comparative rigidity on hepatocirrhosis nodules,and thus may have potential usefulness on estimating the characteristic of hepatoeirrhosis nodules.
出处 《中华超声影像学杂志》 CSCD 北大核心 2010年第1期29-31,共3页 Chinese Journal of Ultrasonography
关键词 超声检查 肝硬化 肝细胞 硬度 超声弹性成像 Ultrasonography Liver cirrhosis Carcinoma, hepatocellular Hardness Elastosonography
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