摘要
目的:探讨口服酪酸梭菌、婴儿型双歧杆菌二联活菌治疗小儿急性腹泻病的疗效。方法:我院2008年1月～2009年5月收治的小儿急性腹泻病患儿120例,随机分为治疗组和对照组各60例。治疗组在一般治疗基础上给予口服酪酸梭菌、婴儿型双歧杆菌二联活菌治疗,对照组在一般治疗基础上给予乳酸菌素治疗,比较两组的有效率、平均止泻时间、平均住院时间。结果:显效率治疗组80.0%,对照组63.3%,两组比较差异有统计学意义(χ2=4.10,P<0.05);平均止泻时间治疗组(3.2±1.5)d,对照组为(4.5±1.3)d,两组比较差异有统计学意义(t=4.69,P<0.01);平均住院时间治疗组(5.5±1.5)d,对照组为(7.8±1.8)d,两组比较差异有统计学意义(t=6.62,P<0.01)。结论:口服酪酸梭菌、婴儿型双歧杆菌二联活菌可缩短小儿急性腹泻的持续时间,止泻效果好,无明显不良反应。
Objective： To study the effects of Oral Clostridium butyricum and Bifidobacterium Powder in children with acute diarrhea. Methods： One hundred and twenty cases of inpatients from January 2008 to May 2009 in our hospital were randomly divided into two groups. Based on the conventional therapy, the treatment group was given Oral Clostridium butyricum and Bifidobacterium Powder and the controlled group only lactobaeiUus. And the two groups were compared in their therapeutic effects, the stopping of diarrhea and the duration of hospitalization. Results： The efficacious rates was 80.0% in the treatment group and 63.3% in the controlled group, and the difference was significant between the two groups （x^2 = 4.10, P 〈 0.05 ）. The days of diarrhea stopping in the treatment group were （3.2 ± 1.5 ）d and the controlled group were （4.5 ± 1.3 ） d, and the difference was significant between the two groups （ t = 4.69, P 〈 0.01 ）. The days of hospitalization in the treatment group were （5.5 ± 1.5 ） d and the controlled group （ 7.8 ± 1.8 ） d, and the difference was significant between the two groups （ t = 6.62, P 〈 0.01 ）. Conclusions： Oral Clostridium butyricum and Bifidobacterium Powder decreased the duration of diarrhea. There is no adverse effect observed.
出处
《儿科药学杂志》
CAS
2010年第1期23-24,共2页
Journal of Pediatric Pharmacy
关键词
酪酸梭菌
婴儿型双歧杆菌
小儿
急性
腹泻
Clostridium butyricum
Bifidobacterium
Children
Acute
Diarrhea
