摘要
目的:进一步提高临床医生对恶性血液病合并侵袭性肺真菌感染的认识,改进治疗措施,减少侵袭性肺真菌感染率、死亡率,提高生存率。方法:分析住院的恶性血液病合并肺侵袭性真菌感染患者52例的一般临床资料、微生物学检查及治疗情况。结果:侵袭性肺真菌感染的发病率不断增高,病原菌以念珠菌为主,52例患者应用抗真菌药物后总有效率为59.6%,死于真菌感染患者19例,死亡率为36.5%。结论:侵袭性肺真菌感染是恶性血液病患者化疗期间严重的并发症和主要的死亡原因之一,早期诊断及经验治疗具有重要意义。
Objective To improve the comprehension of motivation of hematological malignancies accompanied with invasive pulmonary fungal infection, to improve therapeutic measure, reduce fungal infection, mortality rate and increase survival rate. Method Retrospective study of the fungous infection table, nlicrobiology, treatment and outcome of 52 cases who had be clearly diagnosed as hematological malignancies accompanied invasive pulmonary fungal infection. Results Invasive pulmonary fungal infections continued to increase in the incidence,the most commen fungus was C andida,52 patients after application of antifungal agents had a total efficiency of 59. 6% , 19 patients died of fungal infection,and mortality rate was 36.5%. Conclusion Invasive pulmonary fungal infections in patients with hematological malignancies during chemotherapy are important complications and the mainly cause of death. Early diagnosis and empirical treatment is very importance.
出处
《吉林医学》
CAS
2010年第1期20-21,共2页
Jilin Medical Journal
关键词
恶性血液病
真菌
肺
Hematological malignancies
Fungal infection
Pulmonary
