摘要
目的:通过对环状混合痔手术患者进行氢溴酸高乌甲素腰俞穴注射联合静脉滴注以及空白对照的术后肛缘水肿比较,观察高乌甲素在预防痔术后肛缘水肿的作用及其机理。方法:选取需手术的环状混合痔患者30例,随机分为试验组和空白对照组。试验组于腰俞穴注射(1%利多卡因20mL+3～4滴盐酸肾上腺素+高乌甲素2mL),手术后氢溴酸高乌甲素8mg加入5%GNS 500mL静滴日1次,连用3天;空白对照组不使用高乌甲素,其余同试验组。对两组患者术后肛缘水肿情况、并发症及药物不良反应等进行观察比较。结果:在无治疗禁忌的情况下使用高乌甲素者较不使用者环状混合痔术后肛缘水肿发生率低;使用高乌甲素者患者术后创面疼痛情况较不用者轻;未观察到使用高乌甲素增加术后并发症发生;未观察到使用高乌甲素药物不良反应的相关表现。结论:①高乌甲素对环状混合痔术后肛缘水肿有确切的防治作用;②高乌甲素在痔手术中的使用是安全的;③高乌甲素对环状混合痔术后创面疼痛有缓解作用。
Objective：Observing the effect and mechanism of lappaconitine which can prevent from postoperative edema of the edge of the anus after hemorrhoidectomy,through the clinical study to compare 2 groups：a group patients who have crico-mixed hemorrhoids accept injection into Yaoshu point and intervenes drop infusion with lappaconitine,another group is a blank group. Method：Choose 30 patients with crico-mixed hemorrhoids who need operation and divide them into 2 groups in random：experimental group,comparison group. The experimental groups accept injection into Yaoshu point （8mg lappaconitine） before the operation and intervenes drop infusion （8mg lappaconitine add in 5% GNS500mL,iv gtt,qd,use 3 days） after the operation with lappaconitine. The comparison group neither accept injection into Yaoshu point （8mg lappaconitine） nor accept intervenous drop infusion （8mg lappaconitine add in 5% GNS500mL,iv gtt,qd,use 3 days ）. The edema of the edge of anus,complication,and side effects were assessed. Result：The patients who were accepted injection into Yaoshu point and intervenous with lappaconitine had lower incidence of edema than the blank group. Furthermore,the subjective pain response was significantly less in the lappaconitine group. The method of lappaconitine did not increase the incidence of postoperative complications and side effects. Conclusion：①Lappaconitine can prevent from haemorrhoid postoperative edema of the edge of the anus after hemorrhoidectomy;②Lappaconitine can prevent the anorectal postoperative pain; ③It is safe to inject lappaconitine before the operation of hemorrhoidectomy.
出处
《辽宁中医药大学学报》
CAS
2010年第2期143-145,共3页
Journal of Liaoning University of Traditional Chinese Medicine
关键词
高乌甲素
预防
痔手术
肛缘水肿
lappaconitine precaution hemorrhoidectomy edema of the edge of the anus
