摘要
目的观察裸花紫珠片联合阿达帕林凝胶治疗寻常痤疮的临床疗效。方法126例寻常痤疮患者,随机分为阿达帕林凝胶组(A组)62例和裸花紫珠片联合阿达帕林凝胶组(B组)64例,A组外用阿达帕林凝胶治疗;B组在A组的基础上加用裸花紫珠片;两组分别于治疗前、治疗后2 w、4w记录不良反应并判断疗效。结果治疗2 w时A组总有效率为54.84%,B组为70.31%,B组疗效优于A组(P<0.05);治疗4 w时A组总有效率为74.19%,B组为85.94%,B组疗效优于A组(P<0.05);A组的不良反应发生率为35.48%,B组为10.94%,B组明显低于A组(P<0.01)。结论裸花紫珠片联合阿达帕林凝胶治疗寻常痤疮比单用阿达帕林凝胶有更好的疗效和安全性。
Objective To observe the clinical efficacy of callicarpa nudiflora tablet combined with adapalene gel on acne vulgaris. Methods 126 cases of aene vulgaris were randomly divided into adapalene gel group （group A ,62 cases）and the group of callicarpa nudiflora tablet combined with adapalene gel（ group B ,64 cases）. In group A, adapalene gel was administered externally. In group B, on the basis of the treatment as group A,callicarpa nudiflora tablet was applied. Adverse reactions were recorded before treatment,2 w and 4 w after treatment in each group successively and the therapeutic effects were judged. Results In 2 w of treatment,the total effective rate was 54.84% in group A and was 70.31% in group B. The efficacy in group B was superior to that in group A （ P 〈 0.05 ）. In 4w of treatment, the total effective rate was 74. 19% in group A and was 85.94% in group B. The efficacy in group B was superior to that in group A （ P 〈 0.05 ）. The incidence of adverse reaction was 35.48% in group A and was 10.94% in group B. The result in group B was lower than that in group A （ P 〈 0.01 ）. Conclusion The combined therapy of calliearpa nudiflora tablet and adapalene gel is much mote effective and safe than single application of adapalene gel in treatment of acne vulgaris.
出处
《世界中西医结合杂志》
2010年第1期45-47,共3页
World Journal of Integrated Traditional and Western Medicine
关键词
裸花紫珠片
阿达帕林凝胶
寻常痤疮
Callicarpa nudiflora tablet
Adapalene gel
Ache vulgaris
