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糖尿病视网膜病变与血脂、脂质过氧化的关系 被引量:1

The Relation of Diabetic Retinopathy with Blood - Fat and Lipid Peroxidation
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摘要 目的:观察和探讨糖尿病视网膜病变与脂质代谢和脂质过氧化反应的关系。方法:对30名早期糖尿病视网膜病变患者与24名健康人空腹血清中甘油三脂(TC),总胆固醇(TG),高密度脂蛋白—胆固醇(HDL—C),低密度脂蛋白—胆固醇(LDL—C),过氧化物歧化酶SOD)和脂质过氧化物(LPO)的含量进行了检测。结果:发现患者组中TC、TG、LDL—C与LPO均明显高于对照组,而HDL—C与SOD都低于健康对照组。结论:糖尿病引起的脂质代谢紊乱和脂质过氧化反应的增强可能是促进视网病变的危险因素之一。眼科学报1998;14:100—102。 Purpose:To observe and inquire into the relation of diabetic retinopathy with lipid metabolism, and lipid peroxidation. Methods: The contents of triglyceride (TG), total cholesterol (TC), high density lipoprotein - cholesterol (HDL- C), low density lipoprotein - cholesterol (LDL - C), superoxide dismutase (SOD) and lipid peroxide (LPO) of serum were examined and determined both in thirty patients with diabetes in early stage suffering from retinopathy and twenty four healthy people. Results:TG, TC, LDL-C and LPO in patients group were obviously higher than those in the control group, while HDL - C and SOD were lower than those in healthy control group. Conclusion: The disoreder of lipid metabolism and the growing intensity of lipid peroxidation caused by diabetes may be one of the dangerous factors to bring about the retinopathy. Eye Science 1998; 14 :100 - 102.
出处 《眼科学报》 1998年第2期100-102,共3页 Eye Science
关键词 糖尿病 视网膜病变 SOD LPO diabetic retinopathy, superoxide dismutase, lipid peroxide
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  • 1高翔.糖尿病视网膜病变发生的相关危险因素分析[J].眼科研究,2003,21(3):299-301. 被引量:75
  • 2邹杰,郝聪琴,郭建华.尿微量蛋白联合检测对2型糖尿病视网膜病变的诊断意义[J].眼科研究,2003,21(3):311-311. 被引量:5
  • 3中华医学会眼科学会眼底病学组.糖尿病视网膜病变分期标准[J].眼底病,1985,1:42-42. 被引量:187
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