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胰岛素泵在2型糖尿病合并骨折患者围手术期中的应用 被引量:3

Application of the Insulin Pump in Type 2 Diabetic Patients with Fractures in the Perioperative Period
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摘要 目的比较持续皮下胰岛素输注(CSII)与多次皮下胰岛素注射(MSII)两种给药途径对2型糖尿病合并骨折患者血糖控制及手术切口愈合时间的影响。方法将因骨折拟手术的60例2型糖尿病的患者随机分为CSII组和MSII组,每组30例,分别采用CSII、MSII治疗;比较2组患者的血糖控制达标时间、血糖控制水平及手术切口愈合时间的差异。结果2组患者血糖控制均达标,但CSII组降血糖更具优势;CSII组血糖达标时间、手术切口愈合时间短于MSII组,血糖控制水平低于MSII组,差异均有统计学意义(均P<0.01)。结论与MSII相比,CSII能更加迅速、有效地控制高血糖,从而缩短手术等待时间,保障手术切口在正常时间愈合。 Objective To compare the efficacy of multiple subcutaneous insulin Injection (MSII) with continuous subcutaneous insulin infusion(CSII) on glycemic control and healing time of surgical incision in patients with type 2 diabetes mellitus complicated with fracture.Methods 60 patients with type 2 diabetes mellitus and fracture were devided randomly into 2 groups,the CSII group and the MSII group with 30 patients equally.The efficacy of glycemic control and healing time of surgical incision were compared.Results Glycemic controlling conditions were good in both groups,but CSII group reduced more fasting glucose level.Significant differences were observed in glycemic control time and degree and healing time of surgical incision in two groups(all P〈0.01).Conclusion It concluded that CSII group achieved better glycemic control and significant reduction of healing time of the surgical incision.
出处 《江西医学院学报》 2009年第9期61-63,共3页 Acta Academiae Medicinae Jiangxi
关键词 2型糖尿病 骨折 持续皮下胰岛素输注 多次皮下胰岛素注射 围手术期 2 diabetes mellitus fracture continuous subcutaneous insulin infusion multiple subcutaneous insulin injection perioperative period
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  • 1Lauritzen T, Pramming S, Deckert T, Binder C, Pharmacokinetics of continuous subcutaneous insulin. Diabetologia 1983 ; 24 : 326 -329. 被引量:1
  • 2Bode BW, Steed RD, and Davidson PC. Reduction in severe hypoglycemia with long - term continuous subcutaneous insulin infusion in type I diabetes, Diabetes Care 19:324 - 327. 被引量:1
  • 3Glaser B, Leibovich G, Nesjer R, et al. Improved beta - cell function after intensive insulin treatment in severe non - insuline - dependent diabetes.Acta Endocrinologica 1988;118(3) :365- 373. 被引量:1
  • 4Ilkova H, glaser B, Tunckale A, et al. Induction of long - term glycemic control in newly diagnosed type 2 diabetic patients by transient intensive insulin treatment. Diabetes Care 1997; 20:1353 -1356, 被引量:1
  • 5张建功,程桦,黎峰,黄秀琼,李芳萍,陈黎红,严励.血糖控制对2型糖尿病患者胰岛β细胞功能及胰岛素敏感性的影响[J].中华内分泌代谢杂志,2003,19(1):21-24. 被引量:63

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