摘要
目的：研究西洋参水溶性部分的化学成分。方法：西洋参根８０％甲醇提取物的水悬浮液，乙醚、水饱和正丁醇萃取，水溶液部分大孔树脂柱脱糖，硅胶柱反复层析，光谱分析鉴定结构。结果：分得１种单体化合物，确定为丙二酸单酰基人参皂甙Ｒｂ１。另外还分得人参皂甙Ｒｂ１和人参皂甙Ｒｅ。结论：首次发现并鉴定了西洋参中存在的水溶性皂甙。
Objective:To have further comprehension of American Ginseng on the basis of its watersoluble components.Method:The water suspension of 80%methanol extract of American Ginseng was sequentially extracted with ethyl ether and nbutyl alcohol.The saccharides in the watersoluble portion were removed by macroreticular resin column,and three compounds were obtained by silicagel column chromatography.Their structures were confirmed on the basis of spectral analysis(IR,NMR,MALDIMS)melting points and optical degrees.Result:Three compounds were identified as malonyl ginsenosides Rb1, ginsenoside Rb1 and Re respectively.Among them Rb1 and Re are known,while malonyl ginsenoside Rb1 was isolated from American Ginseng for the first time.Its structure was elucidated as (3β,12β)20[(6OβDglucopyranosylβDglucopyranosyl)oxy]12hydroxydammar24en3ylO[6O(carboxyacetyl)βDglucopyranosyl)]βDglucopyranoside.Conclusion:Watersoluble ginsenosides were isolated from the watersoluble extract of American Ginseng suggesting that malonyl ginsenosides exist both in American Ginseng and Ginseng.
出处
《中国中药杂志》
CAS
CSCD
北大核心
1998年第9期551-552,共2页
China Journal of Chinese Materia Medica
关键词
西洋参
水溶性成分
人参皂甙
American Ginseng
watersoluble components
malonyl ginsenosides
