摘要
目的分析医院呼吸病区下呼吸道感染病原菌的分布及耐药情况，为临床合理使用抗生素提供参考依据。方法取2007年1月～2009年2月下呼吸道感染患者深部痰做病原菌培养，按NCCLs标准分离鉴定病原菌并进行药敏试验，统计检出阳性率、病原菌分布比例及敏感率。结果病原菌检出阳性率为48．9％，其中G杆菌占59．1％，G^＋球菌占29．0％，真菌占11．9％；前四位G^-杆菌分别为铜绿假单胞菌、鲍氏不动杆菌、肺炎克雷伯杆菌、大肠埃希菌。肺炎克雷伯杆菌和大肠埃希菌ESBLs发生率分别为49．0％、53．0％。结论呼吸病区感染病原菌以G^-杆菌为主，病原菌耐药性较强，加强细菌药敏实验监测，可为呼吸病区合理选用抗生素提供依据。
Objective To investigate the distribution and antimicrobial resistance of pathogens isolated from lower respiratory tract in respiratory ward for rational antibictics usage clinical pratice. Methods According to NCCLs, pathogens were detected from qualified sputums specimens in lower respiratory tract. The isolated rates, the distribution of pathogenic bacteria and resistance rate were calculated. Results The isolated rate of pathogenic bacteria was 48.9% , of which 59. 1% were Gram - negative bacilli, 29. 0% were Gram - positive cocci, and 11.9% were fungi. The most Gram - negative bacilli were Pseudomonas aeruginosa, Acinetobaeter baumanii, Klebsiella pneumoniae and Escheriehia coli. The rate of extended spectrum β - lactamases（ESBLs） producing Klebsiella pneumoniae isolates and Escheriehia coli ones were 49.0% and 53.0% ,respectively. Conclusion Gram - negative bacilli are the major pathogens of respiratory ward,in which the pathogens show with a high rate of drug - resistance. The result of antimicrobial susceptibility test can guide to cure and control infection in respiratory ward.
出处
《中外医学研究》
2010年第2期14-15,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
呼吸病区
下呼吸道感染
病原菌
耐药性
Respiratory ward
Lower respiratory tract infection
Pathogens
Antimicrobial resistance
